Remodeling of the myocardium in patients with primary aldosteronism (PA) is mediated by the presence of mineralocorticoid receptors on the myocytes and fibroblasts. The goal of this study was to analyze the effect of arterial hypertension and metabolic disorders on the cardiovascular system in patients with PA. We recruited 54 patients with PA, 32 ...

By Andryi Nykonenko, Iryna Zubryk, Oleksandr Podluzhnyi, Olrksandr Molodan, Sergii Bukhtii, Oleksandr Nykonenko

Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cas...

By Roman Moskalenko, Sergiy Danilchenko, Artem Piddubnyi, Oleksandr Kravets, Inna Chorna, Olena Kolomiets, Anatolii Romaniuk

The association of chronic obstructive pulmonary disease and cardiovascular disease was observed during the study of the systemic effects of this disease. Among these patients, the incidence as well as the mortality from cardiovascular disease are significantly higher, while the reduction of cardiovascular risk is an important target for the reduct...

By Borislav Božanić, Milan Radović, Ivana Stanković, Svetlana Apostolović, Tatjana Pejčić, Zorica Ćirić, Lidija Risitić, Milan Rančić

Pelvis is a strong bony-ligamentous structure containing many organs, vessels and nerves. Three forces or a combination of those forces produce pelvic fractures. The main causes of pelvic fractures are traffic accidents and falls from height. Biomechanically pelvic ring can be stable or unstable. Biomechanically unstable pelvic ring after the injur...

By Saša Milenković, Milan Mitković

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

Genetic counselling is a complex process that helps people to understand and adopt medical, psychological and genetic aspects of the disease and enable them to make an appropriate decision. In this framework, we revisited all the existing models for decision-making and suggested their use in the process of genetic counselling, which may lead to mor...

By Marija Lević, Dušanka Krajnović, Valentina Marinković

The maternal mortality rate (MMR) often reflects the development status of one country. This study calculates the incidence rate of maternal mortality and examines the related risk factors in Fars Province, located in South of Iran. Using the surveillance system of Shiraz University of Medical Sciences, we reviewed all childbirth records from 2002 ...

By Alireza Mirahmadizadeh, Fariba Moradi, Elham Hesami, Ahmad Maghsoudi, Amin Mirahmadizadeh, Ali Seifi, Mahsa Kiani, Mohsen Moghadami

Achilles tendon injuries most commonly occur in athletes, but also in the middle-aged population practicing recreational sports. The aetiology of injury and disease of the Achilles tendon has not been completely clarified. While acute injury can be attributed to trauma, research showed that a chronic degenerative process is present in most ruptures...

By Mihajlo Mitrović, Dražen Jelača, Ivana Mitrović

Summary This work investigates the antiradical capacity and potential of Garcinia kola extracts to improve the biochemical markers associated with erectile function and its possible application in clinical treatment. Inhibitory properties of aqueous extract of G. kola on phosphodiesterase-5 (PDE-5), arginase, angiotensin I –converting enzyme ...

By Adebola Busola Ojo, Oluwafemi Adeleke Ojo, Mary Abiola Okesola, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye

The aim of this research was to determine the influence of the experimental program on improving physical fitness in adolescents with intellectual disability (ID). For the needs of a dual prospective study of the cohort, 122 adolescents aged 13 to 17 with mild ID were recruited and then divided into two groups, experimental (EG) and control (CG). T...

By Aleksandar Pejčić, Miodrag Kocić, Dragana Berić, Goran Kozomara, Marko Aleksandrović