This present research work was designed to investigate the potential chemopreventive effects of Annona Muricata on cadmium-induced hepatotoxicity and oxidative neuronal damage in Wistar albino rats. In this study, twenty-eight (28) Wistar albino rats were randomized into four groups, with seven rats each. Group A served as the control and provided ...

By Johnson Oladele, Omowumi Adewale, Olu Oyewole, Mistura Salami, Ganiyat Owoade, Oyedotun Oyeleke

The association of chronic obstructive pulmonary disease and cardiovascular disease was observed during the study of the systemic effects of this disease. Among these patients, the incidence as well as the mortality from cardiovascular disease are significantly higher, while the reduction of cardiovascular risk is an important target for the reduct...

By Borislav Božanić, Milan Radović, Ivana Stanković, Svetlana Apostolović, Tatjana Pejčić, Zorica Ćirić, Lidija Risitić, Milan Rančić

Comorbidity Index (CCI) is a simple method for the demonstration of comorbidity burden. This study aimed to assess the validity and reliability of the CCI among Iranian community-dwelling older adults. This cross-sectional study was carried out on a sample of 600 community-dwelling older adults aged 60 years and over in Tehran, Iran, 2017. A multis...

By Raziye Hosseini, Yadollah Momtaz, Farahnaz Shahboulaghi, Masoome Aghamaleki

Analysis of arterial blood gases is necessary for managing the respiratory and metabolic parameters of patients in the intensive care unit. The aim of this study was to compare the effects of heparin 1000 and heparin 5000 units on arterial blood gases in patients admitted to the intensive care unit. This study was a triple-blinded clinical trial. A...

By Reza Borabadi, Mostafa Rad, Mohammad Rakhshani, Mojtaba Rad

Cervical cancer is considered as a common female genital cancer. It is also recognized as the second most frequent cause of cancer-related death among women. It is estimated that in Iran cervical cancer ranks the 4th most frequent cancer in women. Therefore, with regard to the importance of Pap smear in preventing cervical cancer, together with the...

By Bibi Hoseini, Nematullah Shomoossi, Mohammad Rakhshani, Reihane Beinaghi

Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...

By Nimet Kalkan, Mehmet Tezcan

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

The maternal mortality rate (MMR) often reflects the development status of one country. This study calculates the incidence rate of maternal mortality and examines the related risk factors in Fars Province, located in South of Iran. Using the surveillance system of Shiraz University of Medical Sciences, we reviewed all childbirth records from 2002 ...

By Alireza Mirahmadizadeh, Fariba Moradi, Elham Hesami, Ahmad Maghsoudi, Amin Mirahmadizadeh, Ali Seifi, Mahsa Kiani, Mohsen Moghadami

Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cas...

By Roman Moskalenko, Sergiy Danilchenko, Artem Piddubnyi, Oleksandr Kravets, Inna Chorna, Olena Kolomiets, Anatolii Romaniuk

Summary This work investigates the antiradical capacity and potential of Garcinia kola extracts to improve the biochemical markers associated with erectile function and its possible application in clinical treatment. Inhibitory properties of aqueous extract of G. kola on phosphodiesterase-5 (PDE-5), arginase, angiotensin I –converting enzyme ...

By Adebola Busola Ojo, Oluwafemi Adeleke Ojo, Mary Abiola Okesola, Basiru Olaitan Ajiboye, Babatunji Emmanuel Oyinloye