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Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

As a complex and multidimensional problem, the occupational burnout causes absence, dissatisfaction, badtemper, physical and emotional exhaustion and displacement. This study aimed to investigate the levels of occupational burnout and its components in Mazandaran's hospitals by the kind of their ownership. This descriptive-analytical study was cond...

By Ghahraman Mahmoudi, Jahani Ali, Masoomeh Abdi, Sedigheh Solimanian, Nikbakht Ali, Soheil Ebrahimpour

The purpose of the study was to investigate the effects of Exendin-4 on polycystic ovary syndrome (PCOS) in rats in chronic mild stress medium. For establishing the PCOS model, dehydroepiandrosterone (DHEA) (6mg/100g) in 0.2ml sesame oil was injected subcutaneously to 21-day old rats (n = 67). In addition, 0.2ml sesame oil was injected subcutaneous...

By Burcu Köksal, Sedat Yildiz, Tugba Ozgöcer, Azibe Yildiz, Nigar Vardi, Özlem Barutcu

Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cas...

By Roman Moskalenko, Sergiy Danilchenko, Artem Piddubnyi, Oleksandr Kravets, Inna Chorna, Olena Kolomiets, Anatolii Romaniuk

The aim of the study was to analyze the characteristics {sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and credibility} of tests for microbiological diagnosis of infections caused by Clostridium (C. difficile). The research was done at the Public Health InstituteNiš, the Center for Microbiology du...

By Predrag Stojanović, Niko Radulović, Branislava Kocić, Marina Dinić, Biljana Miljković-Selimović, Kristina Stojanović

Summary Bilomas represent large collections of bile, produced due to a rupture of bile ducts. Most frequently, they are located in the perihepatic tissues, rarely intrahepatic ones. Usually, bile ducts rupture is caused by trauma, spontaneous or iatrogenic, or some underlying disease. The majority of bilomas cases are treated by means of drainage p...

By Aleksandra Radovanović, Miljan Krstić, Jasmina Gligorijević, Aleksandra Veličkov, Marko Stojanović

Breast cancer (BC) is the most prevalent and life-threatening malignant tumor in adult females. Little is known about the association between neuropeptide leptin hormone and development of BC. The aim of the paper was to evaluate the interactive role of neuropeptide leptin hormone among BC Jordanian women with regard to treatment exposure and menop...

By Safa'a Al-Zeidaneen, Mousa Ahmad, Ali Al-Ebous

The present study used scientometrics and word co-occurrence analysis to identify the most important topics and to assess trends in English for medical purposes over time. Documents indexed in Scopus and Web of Science were used to examine various indicators such as keywords, countries, organizations, and authors. Search results were preprocessed t...

By Nematullah Shomoossi, Mostafa Rad, Mansoureh Fiezabadi, Esmaeil Vaziri, Mostafa Amiri

The incidence of thyroid dysfunction in the area of central Bosnia with special reference to hyperthy-roidism was being monitored. Considering that there were disagreements among earlier authors and even their contradictory results, the goal was to determine the percentage ratio between the thyroid hyperfunction and other dysfunctions and to identi...

By Edhem Hasković, Jasmina Marušić, Denis Hasković, Muhamed Fočak, Safija Herenda

The aim of this study was to determine the factors affecting the sexual function of women of reproductive age with reference to the adverse effects of sexual dysfunction in women and its consequences on family life. This research was a cross-sectional study conducted in 2014-2015 and the study population included married women with stable sexual ac...

By Fatemeh Shamsabadi, Zahra Kamali, Mahboobeh Gholami, Toktam Bayat, Akram Poosti, Marzeiyeh Feizi