Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

Teeth are biological markers of maturity, and their eruption into the oral cavity is an essential milestone in an individual's life. Multiple factors have been considered to play a role in the pattern of tooth eruption, including dental caries, fluorides and congenital conditions such as Down's syndrome. The aim of the paper was to determine the ti...

By Varshini Marimuthu, Pushparaja Shetty

The purpose of the study was to investigate the effects of Exendin-4 on polycystic ovary syndrome (PCOS) in rats in chronic mild stress medium. For establishing the PCOS model, dehydroepiandrosterone (DHEA) (6mg/100g) in 0.2ml sesame oil was injected subcutaneously to 21-day old rats (n = 67). In addition, 0.2ml sesame oil was injected subcutaneous...

By Burcu Köksal, Sedat Yildiz, Tugba Ozgöcer, Azibe Yildiz, Nigar Vardi, Özlem Barutcu

The waiting time for patients in the emergency department to receive health services influences many processes in this department. This research aimed to determine the effect of implementation and deployment of emergency severity index (ESI) on the waiting time for patients to receive health services in the emergency department. This quasi-experime...

By Akbar Sarvari, Hosein Habibzadeh, Leyla Alilu, Naser Sheikhi

Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cas...

By Roman Moskalenko, Sergiy Danilchenko, Artem Piddubnyi, Oleksandr Kravets, Inna Chorna, Olena Kolomiets, Anatolii Romaniuk

The association of chronic obstructive pulmonary disease and cardiovascular disease was observed during the study of the systemic effects of this disease. Among these patients, the incidence as well as the mortality from cardiovascular disease are significantly higher, while the reduction of cardiovascular risk is an important target for the reduct...

By Borislav Božanić, Milan Radović, Ivana Stanković, Svetlana Apostolović, Tatjana Pejčić, Zorica Ćirić, Lidija Risitić, Milan Rančić

The review highlights the characteristics of adipose tissue as a metabolically active organ, reveals endocrinous functions of adipose tissue and the role of adipose tissue in immune system’s functioning. The role of obesity in the development of insulin resistance (IR) and diabetes mellitus type 2 and the effect of dyslipidemia on the develop...

By Oksana Tkachenko, Iryna Polishchuk, Nadiya Gorchakova, Hanna Zaychenko

The aim of the study was to analyze the characteristics {sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and credibility} of tests for microbiological diagnosis of infections caused by Clostridium (C. difficile). The research was done at the Public Health InstituteNiš, the Center for Microbiology du...

By Predrag Stojanović, Niko Radulović, Branislava Kocić, Marina Dinić, Biljana Miljković-Selimović, Kristina Stojanović

Summary Team-based learning (TBL) is a well-established instructional strategy that provides students with the chance to apply conceptual knowledge through a series of actions, including pre-class, individual, team class activity, and immediate feedback. The purpose of the present study was to introduce a course of teaching the evidence-based medic...

By Mandana Akbarinejad Mousavi, Mitra Amini, Somayeh Delavari, Ali Seifi

The incidence of thyroid dysfunction in the area of central Bosnia with special reference to hyperthy-roidism was being monitored. Considering that there were disagreements among earlier authors and even their contradictory results, the goal was to determine the percentage ratio between the thyroid hyperfunction and other dysfunctions and to identi...

By Edhem Hasković, Jasmina Marušić, Denis Hasković, Muhamed Fočak, Safija Herenda