Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...

By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi

Oral surgical interventions in the mandibular region require detailed knowledge of the position and course of the mandibular canal. The aim of this study was to determine the most common course of mandibular canal on cone beam computed tomography (CBCT) images in the population of Southeast Serbia. One hundred ninety-four mandibular canals on CBCT ...

By Kosta Todorović, Marija Daković-Bjelaković, Jelena Popović, Aleksandar Mitić, Antonije Stanković, Ana Todorović, Nenad Stošić, Marija Nikolić

Artificial intelligence (AI) offers transformative potential in healthcare management by enhancing predictive analytics, optimizing resource allocation, and supporting clinical decision-making. This study aims to examine the applications of AI in Serbian healthcare institutions, focusing on improving operational efficiency and patient outcomes. The...

By Milić Kimi, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj, Novica Bojanić, Tanja Prodović

Splenic abscess is a very rare extra-intestinal complication of Salmonella infection in the post-antibiotic era with the incidence between 0.14% and 2%. It usually follows bacteremia due to varied etiologies such as trauma, infective endocarditis, intravenous drug abuse, immunodeficiency status (AIDS, diabetes mellitus). An 82-year-old woman presen...

By Milan Pantelić, Tamara Vučinić, Milica Stanucević, Miloš Dujović, Maša Pantelić

Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...

By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević

Glioblastomas (GBMs) are among the most vascularized human tumors and the presence of microvascular proliferation is one of the diagnostic hallmarks of these malignancies. The aim of the present study was to investigate the extent of vascularization and its relation to proliferative activity and the p53 status in GBMs. Tissue samples from 100 selec...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Dragan Dimov

Arteriovenous fistula (AVF) is recommended as the ideal vascular access for hemodialysis (HD), however, there are conflicting opinions when it comes to patients with diabetes mellitus (DM). The aim of the paper was to determine the predictive parameters of AVF maturation for HD in patients with DM. The investigation was organized as a retrospective...

By Radojica Stolić, Marija Milić, Vekoslav Mitrović, Bratislav Lazić, Suzana Milutinović, Snezana Lazić, Kristina Bulatović, Vladimir Mitrović, Andrijana Karanović, Sanja Jovanović

The biliary system is well known for its anatomical variability. Precise imaging and evaluation of the cystic duct are essential for surgeons and interventional radiologists. Herein we reported a rare case of cystic duct variation. Coronal oblique 3D magnetic resonance cholangiopancreatography (MRCP) revealed a posterior spiral course of the cystic...

By Ilija Golubović, Aleksandar Vukadinović, Nebojsa S. Ignjatovic, Miroslav Stojanović

Although diffuse large B-cell lymphoma (DLBCL) represents a paradigm of highly curative disease with a complete remission (CR) rate of ≈ 60%–70% in an upfront setting, the remaining 30%–40% of patients present a relapse/refractory setting. These population are highly critical and amended for salvage treatment approach. Novel appro...

By Ivan Petković, Marija Elez, Aleksandar Popović, Slavica Stojnev, Irena Conic, Miljana Džunić, Dane Krtinić

Inflammatory markers are being investigated as possible predictors of mortality in intensive care population. COVID-19 infection causes significant amount of inflammatory burden. De Ritis score has been suggested as a novel disease marker in conditions characterized with inflammation. In the present work, we aimed to compare De Ritis scores of dece...

By Ibrahim Karagoz, Ital Ilker, Bahri Ozer, Gulali Aktas