The aim of the paper was to determine the efficacy, toxicity and progression free survival with anti-PD-1 immunotherapy pembrolizumab in BRAF wild type metastatic melanoma patients with good performance status (ECOG PS 0-1). From February 2017 to April 2018, 17 patients with BRAF mutant wild type metastatic melanoma were enrolled in the study. Only...

By Ivica Pejčić, Ivan Petković, Ana Cvetanović, Irena Conić

Oils from wild fruits have gained attention due to the presence of the wide variety of natural bioactive lipid components (essential polyunsaturated fatty acids, phytosterols, lipid-soluble vitamins), which have positive effects on human health. The present study describes the extraction of oils from fruits of different plant species, Sambucus nigr...

By Milica Stanković, Svetolik Maksimović, Vanja Tadić, Ivana Arsić

Asystole is a rare primary manifestation in the development of sudden cardiac death (SCD), and survival during cardiac arrest as the consequence of asystole is extremely low. The aim of our paper is to illustrate successful cardiopulmonary resuscitation (CPR) in patients with acute myocardial infarction (AMI) and rare and severe form of cardiac arr...

By Dejan Petrović, Marina Deljanin Ilić, Bojan Ilić, Sanja Stojanović, Milovan Stojanović, Dejan Simonović

TNF-alpha and LT-alpha are involved in the pathogenesis of established lymphoproliferative diseases. Both molecules bind to TNFRI and TNFRII. TNFRI is the major mediator of the TNF pro-apoptotic and proliferative effects and TNFRII might enhance these effects. TNF receptors I and II are normally present on hematopoetic cells. TNFR II is characteris...

By Tatjana Jevtović-Stoimenov, Danica Marković, Milena Despotović, Dušica Pavlović, Gordana Kocić

The aim of this study was to investigate the prognostic significance of troponin I, C-reactive protein and risk factors for the occurrence of complications after myocardial infarction. Troponin I and C-reactive protein values were analyzed in 38% of patients with complications (postinfarction angina, ventricular fibrillation, heart failure and fata...

By Enisa Hodžić, Edhem Hasković, Mirela Duraković, Muhamed Fočak

In Serbia, the first isolates ofC. difficilewere isolated in the Public Health Institute (PHI), Center for Microbiology in Niš, at the end of 2005.The National Reference Laboratory for Anaerobic Infections (NRLA) in PHI Niš confirmed the toxigenic strains that caused the first three registered hospital epidemics in Serbia, in 2006 at ...

By Predrag Stojanović, Branislava Kocić, Gorana Dragovac, Marina Randjelović, Vukica Pantović, Zorica Mitić, Kristina Stojanović

Nanoliposomes represent natural or synthetic nanoparticles made of phospholipids, which may spontaneously aggregate in an aqueous medium. Their use in dermatology and for cosmetic purposes may offer facilitated delivery in skin via enhanced opening of the tight junctions between the epithelial cell monolayers. As far as their use in dermatology is ...

By Hristina Kocić, Milica Stanković, Ivana Arsić

Open elbow dislocations with vascular injury are rare injuries and they most commonly occur after a fall from a high or in sports accidents. Close anatomic proximity of the joint to the neurovascular structures put them at risk of concomitant injury. The aim of this paper is to present the method of treatment of this severe injury.Herein we present...

By Predrag Stojiljković, Milan Jovanović, Ivan Golubović, Milan Mitković, Marko Mladenović, Aleksandar Tošić

In the reference literature, there are a few studies on the development of the lymphatic system in the liver, especially human. This study aims to establish the presence, time of appearance, distribution and representation of expression D2-40 molecule – a marker of lymph vessels endothelial cells during the fetal period of the human liver dev...

By Marko Jović, Ivan Nikolić, Vera Todorović, Aleksandar Petrović, Vladimir Petrović, Tijana Denčić

Academic achievement is one of the most important concepts in the field of education. Although emotional intelligence, as a key factor in academic achievement, has been studied in various studies, yet the results obtained are not in harmony with each other and the topic is yet under debate. In order to fill in this informational vacuum, the present...

By Hossein Ranjbar, Seyed Hossein Khademi, Hossein Namdar Areshtanab