Tumor-Infiltrating Lymphocytes and Breast Cancer: Are Immune Checkpoint Inhibitors Ready for Prime Time in Breast Cancer?
In recent years, results obtained from different studies with large cohorts have revealed a bond between the presence of extensive lymphocytic infiltration and favourable prognostic associations in the early-stage of breast cancer (BC) and high response rates to neoadjuvant chemotherapy. Examiners used tumors from large cohorts of patients who took...
By Ana Cvetanović, Slađana Filipović, Nikola Živković, Miloš Kostić, Svetislav Vrbić, Ivica Pejčić
Topical Anesthetic Misuse in Patients Admitted to Sabzevar Eye Clinic in Iran
Topical anesthetic eye drops are used extensively for ophthalmic examinations but self-treatment and non-technical removal of foreign bodies using tetracaine drops can be hazardous. The present study intended to determine the inadmissible uses of anesthetic tetracaine eye drops, manner of drug obtaining and likelihood of the ocular complications in...
By Ebrahim Shirzadeh, Nematullah Shomoossi, Hasan Abdolahzadeh
Preparation and Characterization of St. John’s Wort Herb Extracts Using Olive, Sunflower and Palm Oils
The aim of the study was to obtain St. John’s wort herb extract (drug:extract ratio 1:5), in a traditional way, using different solvents (sunflower, olive and palm oils) with or without antioxidants (0,02% alpha-tocopherol and 0,01% butylhydroxyanisol). Their characterization was done (organoleptic features, relative density, refractive index...
By Ivana Arsić
Measuring Potential of Preschool Facility Staff to Prevent Early Childhood Caries
The aim of this study was to investigate the possible potential of preschool staff through a newly designed questionnaire and evaluate their role in the prevention of early childhood caries (EEC) in Serbia where extremely high prevalence of this preventable disease was recorded.We preformed a cross-sectional study of 268 preschool staff using speci...
By Danijela Jakšić-Gvozdić, Slobodan M. Janković, Danka Pajović, Sandra Vidojević, Srđan Stefanović, Jasmina R. Milovanović
Morphological Variation of Fissure and Lobe of the Left Lung: A Case Report
The left lung usually has an oblique fissure that divides it into superior and inferior lobes. Some variants in the lobar fissure are well known, but the knowledge of certain uncommon variants will enhance our anatomical understanding and proper identification of the bronchopulmonary segments. Several imaging techniques have been used to describe a...
By Atoni Atoni Dogood, Oyinbo Charles Aidemise, Udoye Ezenwa Patrick
A Rare Case of Primary Breast Mucosa- Associated Lymphoid Tissue Lymphoma
Breast involvement by lymphoma is uncommon and poses challenges in diagnosis. Breast involvement by malignant lymphoma, whether primary or secondary, is a rare event. Primary breast lymphomas account for 0.38% - 0.7% of all non-Hodgkin lymphomas, 1.7% - 2.2% of all extranodal non-Hodgkin lymphomas, and only 0.04% - 0.5% of all breast cancer cases. ...
By Daliborka Marić, Dragan Stojanov, Saša Vujnović, Violeta Kovačević Dragosavljević
Anal Carcinoma: A Series of Cases with a Literature Review
The aim of this study was to analyze the cases of five patients with squamous cell carcinoma (SCC) and to draw attention to the dilemma in the treatment of incontinence on admission of these patients and to present, through a literature review, locations of the surgical treatment. The anal carcinoma is a rare disease which involves different histop...
By Momčilo Stošić, Igor Stojanović, Svetlana Mihajlović, Kosta Zdravković
Phenomenography: A Missed Method in Medical Research
Research is an approach with which human beings can attempt to answer questions and discover the unknowns. Research methodology is something that is determined by the researcher’s attitude toward the universe as well as by the question he is trying to answer. Some essential questions regarding the research process are: “What is the natu...
By Abdolghader Assarroudi, Abbas Heydari
Antidiabetic and Antioxidant Activities of Ethanolic Extract of Dried Flowers of Moringa oleifera in Streptozotocin-induced Diabetic Rats
This study was undertaken to determine the antidiabetic and antioxidant effects of oral administration of ethanolic extract of Moringa oleiferaflower on stretozotocin-induced diabetic rats at 100, 200, and 300 mg/kg b.w. Thirty (30) male experimental albino rats were grouped randomly into six groups: groups A, B, and F are the control, diabetic con...
By Rotimi Olusanya Arise, Oluwaseun Ruth Aburo, Samuel Tobi Farohunbi, Adenike Adebola Adewale
Development and Validation of a Questionnaire about Patient Knowledge of Adverse Effects of Statins
Statins are drugs that are well tolerated, but considering their extensive use, there are still concerns regarding their safety. Knowledge of patients about the side effects of statins has not been adequately studied, although timely recognition of the AES is of vital importance for improving the quality of patient care and reducing morbidity and s...
By Valentina Opančina, Slobodan Janković, Gordana Stanić, Miljan Opančina