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The aim of this study was to analyze the reasons why the guidelines for post-splenectomy vaccination are not being followed. Considering that vaccination reduces the risk of overwhelming post-splenectomy infection, it is important to determine the reasons for inadequate vaccination after splenectomy. Our research was a qualitative study based on in...

By Marko Tanasković, Bozidar Odalović, Slobodan Janković, Nedim Hamzagić

Considering a large number of pathogen factors that enable high virulence of a microorganism such as Staphylococcus aureus (S. aureus), it is essential to see them through the continuous adaptation to the newly acquired mechanisms of the host immune response and efforts to overcome these, allowing the bacteria a perfect ecological niche for growth,...

By Biljana Miljković-Selimović, Marina Dinić, Jovan Orlović, Tatjana Babić

Salicylic acid is a phytochemical with beneficial effects on human well-being. Salicylic acid is a phenolic compound and is present in various plants where it has a vital role in protection against pathogenic agents. Natural sources include fruits, vegetables and spices. The most famous and defined effect of salicylic acid is prostaglandin synthesi...

By Pavle Randjelović, Slavimir Veljković, Nenad Stojiljković, Dušan Sokolović, Ivan Ilić, Darko Laketić, Dušica Randjelović, Nebojša Randjelović

Smoking has many harmful effects on human body. It is well known that smoking is one of the most important risk factors for cardiovascular diseases. Though the ingredients from cigarette smoke stimulate the release of vasoconstrictor and reduce the release of vasodilator substances, the goal of this study was to investigate the acute effects of smo...

By Ana Mrkaić, Suzana Branković, Pavle Randjelović, Milica Veljković, Ivan Pavlović, Mirjana Radenković

Herein we present a 25-year-old female patient with tetralogy of Fallot (TOF). This congenital heart defect is not very common, but it is the most common one among cyanotic heart defects. Treatment of the patients with TF is surgical, with palliative or curative (corrective) intent. Our patient underwent palliative surgery, definitive correction, a...

By Jovana Cvetković, Dragan Đ Đorđević, Milan Šljivić, Marina Deljanin Ilić

01.12.2014. Review article
Histamine and Antihistamines

In recent years, there has been a steady increase in the prevalence of allergic diseases. Allergic immune response represents a complex network of cellular events involving numerous immune cells and mediators. It represents the interaction of innate and acquired immune response. The key role in the immune cascade is taken by histamine, a natural co...

By Nikola Stojković, Snežana Cekić, Milica Ristov, Marko Ristić, Davor Đukić, Maša Binić, Dragan Virijević

Presently, there is very little data on the impact of nicotine and other components of tobacco smoking on the outcome of radioiodine therapy (RIT) in Graves’ disease (GD). Thus, this study was aimed to analyze a possible impact of cigarette smoking on the effect of radioiodine therapy in the patients with Graves’ disease. The study incl...

By Vladan Sekulić, Milena P. Rajić, Marina Vlajković, Slobodan Ilić, Miloš Stević, Ivana Mišić, Milan Božinović

The English language is undoubtedly lingua franca of contemporary globalised world. Besides its widespread use in official communication among different countries, it has also huge impact within the borders of one country as well. Taking into account the fact that nowadays it represents the basic communicative tool in the field of medical science i...

By Nataša Milosavljević, Zorica Antić

Many of the children referred to the emergency complain of head trauma. Children usually require sedition to reduce their failure and fear because of high activity and fear of performing computed tomography (CT). Dexmedetomidine and Midazolam belong to short-acting drugs for this purpose. This study aimed to compare the effect of the above mentione...

By Adel Hosseini, Shamila Noori, Abolfazl Mostafavi, Ali Sharami, Seyyed Abbas Hashemi, Hojjat Derakhshanfar, Farzad Bozorgi

Economic evaluations in health economics are analytical methods used for the analysis of costs and consequences of two or more alternative health programs or interventions. These analyses involve identification, measurement, evaluation and comparison of costs and consequences. Whenever there are two alternative health programs or treatments that le...

By Vladica Veličković, Aleksandar Višnjić, Jovan Mihajlović