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Developmental dysplasia of the hip (DDH) means a distinct dislocation (lateralisation and cranialisation) of the femoral head from the poorly developed (hypoplastic and steeper) acetabulum.   The aim of the paper was to establish, in a retrospective and prospective study conducted in the period between January 1, 2006 and December 31, 2010, th...

By Predrag Grubor, Milan Grubor, Marinko Domuzin, Ivan Golubović

Literature data on the association between the incidence of ruptured abdominal aorta and seasons are contradictory. The influence of climatic factors on the rupture of abdominal aorta is geographically dependent. The aim of this research was the investigation of the connection between the incidence of ruptured abdominal aorta and seasons at the ter...

By Zoran Damnjanović, Milan Jovanović, Predrag Đorđević, Nenad Ilić, Irena Janković, Igor Smiljković, Nikola Đorđević, Dragutin Grozdanović

Spermine Oxidation Products Induce Mitochondrial Alterations on Tumor CellsCytotoxic products of polyamines generatedin situby an enzyme-catalyzed reaction may be useful as a new avenue in combating cancer. This study demonstrates that multidrug resistant (MDR) cancer cells (colon adenocarcinoma and melanoma) are significantly more sensitive than t...

By Enzo Agostinelli

20.06.2011. Original article
Childhood Asthma and its Comorbidities

Numerous comorbidities are frequently associated with asthma and may influence the clinical expression and severity of asthma. The aim of our study was to determine the presence and prevalence of other diseases in children with asthma, both of allergic and non-allergic origin. The study included 974 non - hospital patients, of whom 669 had asthma, ...

By Sanja Dimitrijević, Snežana Živanović, Ljiljana Šaranac

Obsessive-compulsive disorder (OCD) is defined by the presence of either obsession or compulsion that is severe enough to be time consuming or to cause marked distress or significant impairment. At some point during the course of the disorder, the person recognizes that the obsessions and compulsions are excessive or unreasonable. Twenty-one patien...

By Lydia Sushevska, Nichola Olumchev, Mirjana Saveska

20.06.2011. Original article
Treatment of Perforative Peptic Ulcer

Perforation of peptic ulcer (PPU) is the most frequent complication of peptic ulcer disease. PPU is a serious complication which demands urgent diagnostic procedures, reanimation and surgical intervention. The aim of this study was to establish the frequency of PPU, diagnostic and therapy procedures, time and kind of surgical methods, as well as mo...

By Ivana Đorđević, Aleksandar Zlatić, Irena Janković

Abdominal aortic aneurysm (AAA) is a complex disease defined as a pathologic dilatation of the infrarenal aorta that is often accompanied by significant superimposed atherosclerosis, inflammation and thrombosis. AAAs are a significant cause of morbidity and mortality in the United States and worldwide. While some patients may present with lower bac...

By Philip Tsao, Ivana Burazor

Between 1996 and 2004, a total of 708 patients were enrolled in the AML ´96 and 2002 studies of the East German Study Group. Of those, 138 patients (19.5%) had unfavourable cytogenetics defined as complex karyotype, del (5q)/-5, del (7q)/-7, abn (3q26) and abn (11q23). Seventy-seven (56%) patients achieved CR1 after induction chemotherap...

By Nadežda Basara, Antje Schulze, Herbert Sayer

Scanty information is available regarding the clinical characteristics, quality of life (QoL) profile and manometric findings in unselected newly diagnosed cases of achalasia. Fifty-six consecutive cases of newly diagnosed achalasia have been characterized regarding the symptoms when a standardized protocol was applied, to which was added a more de...

By Srđan Kostić, Magnus Ruth, Ann Kjellin, Lars Lundell, Erik Svartholm, Mats Andersson, Hans Lönroth

High performance liquid chromatography with diode array detection (HPLC -DAD) was used to study the autoxidation of gallic acid in alkaline aqueous solutions and the influence of Mg(II) ion on this process. At pH 10, one main autoxidation product was determined, and based on the data obtained in this study its structure was proposed to some kind of...

By Goran Nikolić, Aleksandar Veselinović, Žarko Mitić, Slavoljub Živanović