Breast cancer (BC) represents a globally significant health issue, with incidence rates varying worldwide. Radiotherapy is crucial in treating BC, however, it can cause adverse effects, including skin reactions. The aim of this research was to evaluate the impact of two different radiotherapy fractionation regimens on the occurrence and severity of...

By Milica Radić, Andrija Jović, Ana Cvetanović, Ivan Petković, Dane Krtinić, Katarina Krasić, Sandra Radenković, Slavica Stojnev, Irena Conić

Retinitis pigmentosa (RP) is a diverse group of inherited retinal diseases characterized by the gradual degeneration of rod and cone photoreceptors in the retina. RP is primarily inherited, with numerous genetic mutations implicated in its pathogenesis. The aim of this study was to summarize the findings of studies related to genes implicated in re...

By Olivia Narváez, Zerón Mendieta, Orlando Torres, Magally Escobar, Martha Trujillo-Güiza

Splenic abscess is a very rare extra-intestinal complication of Salmonella infection in the post-antibiotic era with the incidence between 0.14% and 2%. It usually follows bacteremia due to varied etiologies such as trauma, infective endocarditis, intravenous drug abuse, immunodeficiency status (AIDS, diabetes mellitus). An 82-year-old woman presen...

By Milan Pantelić, Tamara Vučinić, Milica Stanucević, Miloš Dujović, Maša Pantelić

Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...

By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi

Rheumatoid arthritis (RA) is a systemic autoimmune disease that can cause destructive joint disease and progressive disability. The diagnosis of RA is based on laboratory and clinical evidence, which includes the analysis of inflammatory markers, hematological, and biochemical parameters. Fifty patients diagnosed with RA without methotrexate (MTX) ...

By Maja Mitrašinović-Brulić, Ema Maslo, Muhamed Fočak, Damir Suljević

Wernicke encephalopathy is a rare acute/subacute neurological disorder, commonly caused by prolonged thiamine deficiency in patients who chronically consume alcohol. According to the Caine classification criteria, the clinical diagnosis of this encephalopathy involves at least two of the following four signs: nutritional deficiency, oculomotor dysf...

By Aleksandra Lučić-Prokin, Vladimir Galić, Timea Kokai-Zekić, Vedran Žigić

Zinc is a trace element involved in insulin metabolism, including its production, storage, and release. Selenium is regarded as a vital micronutrient for humans. It participates in insulin signaling and control. Zinc and selenium may be possibly linked to insulin resistance; however, these relationships have not been well investigated. Therefore, w...

By Fahad Hammadi, Hamdan Bader, Al-Mayah Sharhan

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al

Venomous snakebites in Serbia are neither too frequent nor extremely dangerous. Nevertheless, some can lead to complications or even death. On December 24, 2023, a young man was admitted to hospital after being bitten by a snake, believed to be Vipera ammodytes. He was in a state of shock, unconscious, with unmeasurable blood pressure. Having recei...

By Slađana Pavić, Sonja Nikolić

Burns represent one of the leading causes of morbidity and mortality in children. Aim. Aim of this review is to gain better understand of the pathophysiological changes and assessment of the severity of burn injuries in different ages of pediatric patients, which may help in early implementation of appropriate therapeutic procedures and improvement...

By Vesna Marjanović