Restoring the morphological and functional integrity of damaged or lost teeth and replacing them with suitable materials remains a significant challenge in modern dentistry. A continuous development of new restorative materials aims to improve mechanical properties, aesthetic outcomes, and longevity of dental restorations, while minimizing adverse ...

By Ana Pejčić, Milena Kostić, Ivana Stankovic, Radmila Obradovic, Marija Bradic-Vasic, Marija Đorđević, Marko Igic, Nikola Gligorijević

Inflammatory markers are being investigated as possible predictors of mortality in intensive care population. COVID-19 infection causes significant amount of inflammatory burden. De Ritis score has been suggested as a novel disease marker in conditions characterized with inflammation. In the present work, we aimed to compare De Ritis scores of dece...

By Ibrahim Karagoz, Ital Ilker, Bahri Ozer, Gulali Aktas

The aim of this study was to examine whether green tea and bilberry have beneficial effects on secondary hyperlipidemia developed due to gentamicin-induced renal impairment. GM group of rats was treated with gentamicin only, GT group was given green tea only, B group received bilberry only, while C group was given saline only. GT+GM group received ...

By Milica Veljković, Nikola M. Stojanović, Tanja Džopalić, Dragana R. Pavlović, Dušan Sokolović, Milan Petković

Numerous clinical trials have proven the connection between two glandular organs, in this case, the breast and the thyroid gland. The occurrence of breast cancer (BC) is increased in patients with autoimmune thyroid disease (Hashimoto's thyroiditis and Graves' disease). Patients with Graves' disease have a significantly smaller number of described ...

By Tijana Veljković, Dragana Bubanja, Nataša Zdravković, Željko Todorović, Radiša Vojinović, Mladen Maksić

Anatomically insignificant stenosis of coronary arteries obtained on coronary angiography, in numerous cases can show hemodynamic significance and as such cause ischemic myocardial changes. The goal was to assess the diagnostic accuracy of myocardial perfusion scintigraphy (SPECT MPI) in the detection of hemodinamically significant coronary artery ...

By Miloš Stević, Marina Vlajković, Filip Veličković, Tamara Anđelković, Nina Topić

Epidermal growth factor receptor (EGFR) is one of the key tumor markers of non-small cell lung cancer (NSCLC) and a guideline for the choice of therapeutic procedures. The research aims to evaluate the methods used in the investigation of EGFR variants in NSCLC cell lines and combined research (NSCLC cell lines and patient samples) in the last deca...

By Jovana Todosijević-Jovanović, Jasmina Obradović

Microencapsulation technology can be used for the protection of Alpha-tocopherol from degradation in unfavorable environments and enhancement of bioavailability and shelf-life of vitamin E. The aim of this study was the synthesis and characterization of alginate microparticles for the oral delivery of a-tocopherol. Four different formulations of Al...

By Milja Živković, Ana Barjaktarević, Marina Tomović, Anđela Uštević

Chronic apical periodontitis represents dynamic continuation of the presence of endodontic infection in the root canal system of the tooth, when the innate and acquired immune responses are activated and various cells and inflammatory mediators are recruited, which cause the consequent destruction of periapical tissues and the development of periap...

By Jelena Popović, Tatjana Cvetković, Tanja Džopalić, Aleksandar Mitić, Marija Nikolić, Radomir Barac, Nenad Stošić, Antonije Stanković

During the SARS-CoV-2 pandemic, there was a significant number of cases accompanied by thrombosis. The precise pathophysiological mechanism remains unclear. The importance of the fibrinolytic mechanism in maintaining physiological hemostasis led us to explore its potential contribution to COVID-19-induced thromboembolism. This study aimed to identi...

By Igor Spasić, Dejan Dobrijević, Biljana Vučković

Polypharmacy can increase the risk of side effects and cause adverse drug interactions with a significant impact on the course of the basic disease. The aim of the study was to determine the frequency of polypharmacy and examine its impact on the risk of drug-drug interactions in patients with rheumatoid arthritis (RA). The research was conducted i...

By Nikola Krstić, Nikola Stefanović, Milan Petronijević, Ivana Damnjanović