RELIABILITY OF ELISA TEST IN THERAPEUTIC DRUG MONITORING OF ADALIMUMAB AND INFLIXIMAB IN PEDIATRIC INFLAMMATORY BOWEL DISEASE
Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...
By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić
NIZON-ISIDOR SYNDROME, A RARE GENETIC DISEASE WITH LATE DIAGNOSIS PRESENTING WITH AUTISM SPECTRUM DISORDER: A CASE REPORT
Nizon-Isidor syndrome (NIZIDS) is a rare genetic disorder associated with mutations in the MED12L gene and is usually characterized by a distinctive facial appearance, neurodevelopmental delay, autism spectrum disorders (ASD), and chronic gastrointestinal symptoms (GIS). In this case report, we emphasize the importance of early evaluation of geneti...
By Mehmet Semih Demirtaş, Yakup Köylü
MONITORING MICROCIRCULATION IN THE PALATAL MUCOSA BENEATH AN UPPER COMPLETE DENTURE USING A LASER DOPPLER FLOWMETRY: A PRELIMINARY STUDY
Older edentulous adults often rely on mucosa-supported complete dentures (CDs) due to limitations that preclude implant therapy. Although an adequate retention of maxillary CD is essential for functional efficiency, compression of the palatal mucosa during impression making may compromise palatal mucosal microcirculation during denture wear. T...
By Petar Tekić, Stefan Vulović, Marija Milić, Marko Igić, Milena Kostić, Aleksandra Popovac, Ivica Stančić, Aleksandra Milić Lemić
18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY WITH COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF LOEFFLER'S ENDOCARDITIS: A CASE REPORT
Loeffler's endocarditis (LE) is a rare form of inflammatory cardiomyopathy. The condition arises from diffuse eosinophilic infiltration of the endomyocardium, followed by eosinophil degranulation and progressive tissue fibrosis. The aim of this case report is to present a rare form of restrictive cardiomyopathy, LE, in a young female patient, and t...
By Milica Kotur, Nikola Pantić, Lenka Grujičić, Isidora Grozdić-Milojević, Dragana Šobić-Šaranović, Vera Artiko, Strahinja Odalović
ORAL HEALTH IN CHILDREN WITH TYPE 1 DIABETES MELLITUS IN RELATION TO METABOLIC CONTROL
Diabetes mellitus is one of the most common chronic diseases in childhood. The aim of this study was to evaluate the oral health of children with type 1 diabetes in relation to the level of glycemic control. 87 children aged 10 to 15 participated in the study, divided into two groups according to the value of glycosylated hemoglobin (HbA1c): 34 chi...
By Mirjana Djuričković, Aleksa Djuričković
PLACENTAL PROTEIN 14 AS A POTENTIAL BIOMARKER FOR DIAGNOSIS OF PRETERM PRELABOR RUPTURE OF MEMBRANES
Preterm prelabor rupture of membranes (PPROM) is a major cause of neonatal morbidity and mortality. Placental Protein 14 (PP14), a glycodelin glycoprotein, has emerged as a potential biomarker for the diagnosis of PPROM. The study aimed to evaluate the diagnostic accuracy of PP14 in detecting fetal membrane rupture. This case-control study was cond...
By Alaa Ali Rahi, Miami Abdul Hassan Ali
THERAPEUTIC POTENTIAL OF MEDICINAL PLANTS IN POLYCYSTIC OVARY SYNDROME: A NARRATIVE REVIEW
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects the reproductive, metabolic, and psychological health of women of reproductive age. Conventional therapies for PCOS primarily focus on symptom management; however, their associated side effects have led many women to explore complementary approaches. This review aimed to ...
By Gala Žarković, Vladimir Jakovljević, Saša Raičević, Angela Ćorić, Rosa Čukić Ćorović, Nikola Jović, Jovana Joksimović Jović
REGULATION OF APPLIED ARTIFICIAL INTELLIGENCE IN BIOMEDICAL ENGINEERING AS A HIGH-RISK ARTIFICIAL INTELLIGENCE SYSTEM IN THE EU AI ACT
Artificial intelligence (AI) represents a global phenomenon changing all spheres of human life. Biomedical engineering is no exception, as many AI systems are applied to biomedical engineering inventions. The European Union has enacted the new EU AI Act, one of the world’s first laws on AI. The main topic of this research is to examine what c...
By Srdjan Djordjević, Nikola Ivković, NIkola Milosavljević
FUSOBACTERIUM SPECIES IN ORAL AND MAXILLOFACIAL INFECTIONS: MICROBIAL ECOLOGY, COMMUNITY DYNAMICS, AND ANTIMICROBIAL SUSCEPTIBILITY
Oral and maxillofacial infections (OMIs) are polymicrobial conditions in which obligate anaerobes, particularly Fusobacterium spp., play an important pathogenic role. Despite their relevance, the species distribution, ecological context, and antimicrobial susceptibility of Fusobacterium in OMIs remain incompletely understood. This study aimed to ch...
By Kinga Markowska-Michalak, Marta Mierzkowska, Edyta Podsiadły, Anna Majewska
THE IMPACT OF ANTENATAL CORTICOSTEROID ADMINISTRATION ON EARLY OUTCOME PARAMETERS AND LABORATORY FINDINGS IN NEONATES
This study evaluates the impact of antenatal corticosteroid (ACS) administration on early neonatal outcomes and laboratory parameters in preterm infants born at 28–34 gestational weeks. It assesses the effects of ACS on early morbidity, respiratory support, NICU admission, and metabolic changes reflected in laboratory parameters. A retrospect...
By Svjetlana Mikulić, Marjana Jerković Raguž