Incremental cost/effectiveness ratio (ICER) of many drugs for rare diseases is often much higher that the accepted cost/effectiveness threshold for reimbursement, primarily due to their extremely high prices, raising the question of their availability. The aim of this article was to review necessary adjustments of methods used for cost/effectivenes...

By Branislava Raičević, Slobodan Janković

Collision tumors occur when two tumors of different histological origin develop simultaneously at the same site, such as sarcoma and carcinoma combinations, carcinoma and lymphoma combinations, or others. Notably, collision tumors are less common in the lungs compared to other organs. A 65-year-old woman with a history of surgically and chemotherap...

By Džemila Alić, Marina Marković, Slobodanka Mitrović, Milena Ilić, Ajtana Bajrović, Jelena Savić, Marija Spasojević, Dalibor Jovanović

The metabolism and effects of the abuse of psychoactive substances are not yet fully understood, but it is evident that they represent a tremendous risk to the health of individuals. This paper aims to present a review of published results on the impact of psychoactive substance abuse on kidney function. PubMed and MEDLINE databases were used to se...

By Radojica Stolić, Marija Milić, Vekoslav Mitrović, Andrijana Karanović, Kristina Bulatović, Dragiša Rašić, Milica Mirović, Branka Mitić

Rothmund-Thomson syndrome (RTS) or congenital poikiloderma is a rare autosomal recessive genodermatosis with involvement of many systems. The risk of mesenchymal malignancy is high in this disease which is accompanied by skin findings such as skin atrophy, hypo-hyperpigmentation, short stature, growth retardation, hypogonadism, nail and tooth dyspl...

By Sebahattin Memis, Mehmet Demirtas

Knowing the precise position of the mental foramen is of great clinical importance in dentistry due to significant anatomical structures that pass through this foramen. The aim of this study was to examine the sexual dimorphism of the horizontal and vertical position of the mental foramen in relation to constant anatomical landmarks in the populati...

By Antonije Stanković, Jelena Popović, Marija Daković-Bjelaković, Aleksandar Mitić, Nenad Stošić, Marija Nikolić

People with circadian rhythm disturbances are at an elevated risk of mental disorders, and conversely, those with mental disorders are more susceptible to the circadian disruption. A steady circadian cycle of sleep and wakefulness that is phase-shifted relative to the prior local solar time may be characterized by a short endogenous circadian perio...

By Dmytro Boiko, Oksana Mats, Anastasiia Shkodina, Andrii Skrypnikov

The length of tooth enamel conditioning time and the size of bracket bases are some the factors influencing the bond strength between the two adherents. The aim of this study was to compare the shear bond strength (SBS) between two different types of bonded metal brackets and acid-etched enamel surface in two different times. Forty extracted human ...

By Vladimir Mitić, Ana Todorović, Aleksandar Mitić, Kosta Todorović, Milan Miljković

Patients who undergo kidney transplantation can encounter significant changes in body composition because of weight gain caused by fat mass accumulation and muscle mass loss, resulting in poor graft outcomes. The study aimed to investigate the impact of different obesity parameters on graft function in kidney transplant recipients. A cross-sectiona...

By Zorica Dimitrijević, Ina Konstantinović, Jelena Ranđelović, Tamara Vrećić, Mina Cvetković, Karolina Paunović, Goran Paunović, Branka Mitić

Postoperative delirium is defined as an acute state of confusion that develops within hours or days after surgical intervention. With the global aging of the world population, the number of geriatric patients who will undergo surgery is on a steady rise, increasing therefore the possibility of postoperative delirium. The primary aim of this study w...

By Marija Stošić, Velimir Perić, Jelena Živadinović, Aleksandar Kamenov, Vladimir Stojiljković, Dragan Milić, Milan Lazarević, Aleksandar Nikolić, Dalibor Stojanović, Mlađan Golubović

Voice is an acoustic phenomenon that must be viewed multidimensionally. In the quantitative assessment of voice characteristics, the use of acoustic parameters becomes a necessary method of analysis. The aim of the paper is to examine whether there are differences in the acoustic parameters of the voice (the average value of the fundamental frequen...

By Ivana Ilić-Savić, Mirjana Petrović-Lazić