Homocysteine is an amino acid that is formed in the metabolism of methionine as the quantitatively most important metabolite. Its chemical structure has been known for 90 years and its biological roles are still being investigated. Under normal conditions, homocysteine is present in plasma at the concentration of 5 - 9 mmol/l. When the cell capacit...

By Bojana Miladinović, Vladana Živković, Dušanka Kitić, Maja Nikolić

Standard biomarkers for the diagnosis and follow-up of chronic kidney disease patients are appropriate neither in early diagnostics, adequate follow-up and progression assessment nor in complication development risk assessment. For that reason, a search for new, more suitable biomarkers continues. Various studies suggested microRNAs as a potential ...

By Vladana Stojiljković, Nikola Stefanović, Marija Vukelić-Nikolić, Branka Đorđević, Jelena Bašić, Gordana Kocić, Tatjana Cvetković

Necrotizing soft tissue infections are actually the diseases with a severe outcome characterized by the progression of soft tissue inflammation with a catastrophic prognosis and the risk of major functional consequences. Only prompt diagnosis and prompt care, including prompt administration of appropriate antibiotic therapy and surgical treatment, ...

By Mladen Kasalović, Gojko Igrutinović, Zlatan Elek, Aleksandar Jakovljević, Nikola Miljković, Milica Milentijević

The aim of the present study was to compare the effect of volatile induction and maintenance of anesthesia (VIMA) and target controlled infusion (TCI) on cardiovascular stability in New York Heart Association (NYHA) grade II patients who underwent laparoscopic cholecystectomy. In the present study, 90 patients were randomized into two groups depend...

By Biljana Stošić, Marija Stošić, Jelena Živadinović, Ines Veselinović

The incidence of liver cancer is increasing globally. Fatty acids in lipid metabolism are associated with cancer risk by maintaining cancer cell membrane structure and transducing cancer signaling, and their increased synthesis promotes tumor growth, angiogenesis, and tumor metastasis. After identification of the ELOVL3 gene involved in fatty acid ...

By Yiyang Chen, Wanbang Zhou, Yiju Gon, Xi Ou

Since 1999 continuous glucose monitoring (CGM) has been used to measure the amount of glucose in the interstitial fluid. CGM is crucial when it comes to developing the ambulatory glucose profile and giving information on time spent in range (TIR), percentage of time spent above and below range, as well as variability. It was in 1992 that Campbell e...

By Milovan Stojanović, Milica Pešić, Stevan Ilić, Marina Deljanin-Ilić, Vojislav Ćirić

The aim of the paper was to evaluate the AgNOR parameters for the discrimination of benign from malignant breast tumors via a new approach - the total AgNOR area/nuclear area (TAA/NA). Three groups, consisting of control (n = 14), benign (n = 18) and malignant (n = 28) participants were included in the study. The AgNOR staining technique was perfor...

By Mehmet Koksal, Serap Dogan, Recep Eroz, Figen Ozturk, Ahmet Ozturk, Nurhan Cucer

Traumatic injury to the cervical segment of the spinal cord causes disability and quadriplegia. Upper extremity mobility and restoration of hand function for people with quadriplegia is a priority. With coordinated electrical stimulation of peripheral muscles and nerves, known as functional electrical stimulation (FES), this is possible. Upper limb...

By Ranka Ogurlić, Anka Vukićević, Emira Švraka

Lemon balm has been used for centuries due to its strong sedative, antimicrobial and spasmolytic effects. Besides different types of extracts and essential oils, hydrolates (by-products obtained during essential oil extraction) are preparations of aromatic medicinal plants with potential pharmacological activity. To estimate Melissa officinalis lea...

By Nikola Stojanović, Sara Mladenović, Bogdan Stojiljković, Aleksandar Marković, Dragana Pavlović, Pavle Ranđelović, Jelena Zvezdanović, Ljiljana Stanojević

Aesthetic appearance is one of the major concerns in adolescent idiopathic scoliosis (AIS) patients and its improvement is one of the main treatment's goals. Poor trunk appearance is associated with reduced quality of life in adolescents with idiopathic scoliosis. To review instruments that have been created to evaluate poor trunk appearance in the...

By Vesna Živković, Lidija Dimitrijević, Hristina Čolović, Dragan Zlatanović, Marija Spalević, Nataša Savić