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The COVID-19 pandemic caused by the SARS-CoV-2 virus has led to significant public health problems, severe complications, and functional impairment in persons who have recovered from this disease. A 60-years-old male deconditioned patient was transferred from Corona 4 Center to the Center for Physical Medicine and Rehabilitation of the University C...

By Vesna Grbović, Aleksandra Jurišić-Škevin, Nataša Marković, Kristina Mladenović, Marina Petrović-Stanković, Kristina Mitrović, Dejan Aleksić, Stefan Simović, Željko Todorović, Nataša Zdravković-Petrović

Systemic lupus erythematosus (SLE) represents a multisystemic disease characterized by antibody production, complement activation, and immune complexes deposition. Certain types of malignancies occur more often, and conversely, some of them occur less often in SLE patients. Mucosal melanoma of the anorectal region represents a rare form of melanoma...

By Aleksandar Popović, Ivan Petković, Andrija Rančić, Aleksandra Dimitrijević, Vesna Brzački, Stefan Stankov, Andrija Jović, Sonja Stojanović

When receiving anesthesia, patients with obstructive sleep apnea (OSA) are more likely to experience perioperative difficulties than those without this diagnosis. Aim. The aims of the paper were to highlight the correlation between OSA and increased risk of perioperative complications and present possible complications and pathophysiological mechan...

By Zoran Stamenković, Lidija Ristić

Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020....

By Vahidreza Borhaninejad, Maryam Saber

Recently, hemoglobin A1c (HbA1c) has been suggested as a predictor of mortality and poor clinical outcome in patients with trauma. The aim of this study was to evaluate the relationship between HbA1c values and clinical outcome in patients with traumatic brain injury (TBI). In a cross-sectional study, a total of 133 TBI patients referred to the eme...

By Sajad Shafiee, Misagh Shafizad, Dorsa Marzban, Samad Karkhah, Mohammad Ghazanfari, Amir Zeydi

The coronavirus caused the pandemic COVID-19 that has an extensive influence in the world. The virus enters and infects body cells through superficial protein ACE2. Each cell possessing ACE2 is potentially vulnerable to this virus. Since the respiratory system is exposed to the environment and has ACE2, it is one of the first candidates infected by...

By Roshanak Ghobadian, Hossein Khaleghzadeh-Ahangar

This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...

By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye

Neutrophil-lymphocyte ratio (NLR) is one of the laboratory biomarkers used in clinical practice to predict severity and mortality of acute pancreatitis (AP), however, there is currently insufficient information about the changes of NLR in the dynamics in relationship with other clinical and laboratory data. To assess the relationship between NLR va...

By Tetiana Formanchuk, Hryhoriy Lapshyn, Mariya Pokidko, Andrii Formanchuk, Igor Vovchuk

The key links in the etiology and pathogenesis of periodontal tissue diseases are the quantitative and qualitative changes in the composition of the microflora of the oral cavity, with the simultaneous deterioration of oral hygiene, and reduction of local and general immunity, which occurs more often in the presence of somatic diseases. The aim of ...

By Iryna Lisetska, Mikola Rozhko

Non-steroidal anti-inflammatory drugs (NSAIDs) are ranked first among the world's effective anti-inflammatory and analgesic drugs with anticipated side effects. That is why the prevention of development of adverse reactions associated with NSAIDs, in particular, of those related to their ulcerogenicity, remains a serious global problem. Aims. To ch...

By Fedir Hladkykh