Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020....

By Vahidreza Borhaninejad, Maryam Saber

Toxoplasmosis modifies various hormones and cytokines in the infected hosts which may result in several disorders. This study was conducted to assess testosterone, DHEA, and prolactin concentration levels among Toxoplasma gondii infected and uninfected infertile couples. Blood samples were collected and sera were separated. The sera were analyzed f...

By Masomeh Bayani, Narges Kalantari, Sedigheh Esmailzadeh, Salman Ghaffari, Soleiman Mahjoub, Faezeh Ghofrani, Taraneh Ghaffari

The lateral medullary syndrome is a neurological disease caused by ischemia in the lateral part of the medulla oblongata and is the most common form of brainstem infarction. Dysphagia is a common and clinically significant symptom of this disease because it is closely associated with the risk of recurrent pneumonia, malnutrition, dehydration, and a...

By Mile Vuković, Mirna Zelić

The coronavirus caused the pandemic COVID-19 that has an extensive influence in the world. The virus enters and infects body cells through superficial protein ACE2. Each cell possessing ACE2 is potentially vulnerable to this virus. Since the respiratory system is exposed to the environment and has ACE2, it is one of the first candidates infected by...

By Roshanak Ghobadian, Hossein Khaleghzadeh-Ahangar

This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...

By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye

The objective of this narrative review was to describe the versatile links between mental status and sleep in patients with Parkinson's disease. We searched randomized controlled studies, observational studies, meta-analyses, systematic reviews, and case reports written in English in PubMed during 2015 - 2021. Additionally, to ensure the completene...

By Anastasiia Shkodina, Tymur Iengalychev, Kateryna Tarianyk, Dmytro Boiko, Nataliia Lytvynenko, Andrii Skrypnikov

The key links in the etiology and pathogenesis of periodontal tissue diseases are the quantitative and qualitative changes in the composition of the microflora of the oral cavity, with the simultaneous deterioration of oral hygiene, and reduction of local and general immunity, which occurs more often in the presence of somatic diseases. The aim of ...

By Iryna Lisetska, Mikola Rozhko

Non-steroidal anti-inflammatory drugs (NSAIDs) are ranked first among the world's effective anti-inflammatory and analgesic drugs with anticipated side effects. That is why the prevention of development of adverse reactions associated with NSAIDs, in particular, of those related to their ulcerogenicity, remains a serious global problem. Aims. To ch...

By Fedir Hladkykh

Chemotherapy may cause various nail damages, including chromonychia, melanonychia, onycholisis, and onychomadesis. Melanonychia is characterized by melanin-derived brown-to-black nail pigmentation. It may occur as a result of nail matrix melanocytic activation or melanocytic hyperplasia, and nail invasion by melanin-producing pathogens. We present ...

By Ivan Petković

Breastfeeding is the most important way to feed a newborn, infant and a young child. Lactogenesis is the ability of secreting milk from the mammary gland and includes secretory initiation and activation. The birth of the placenta and decrease in progesterone levels stimulate an increase in prolactin levels and the secretion of milk from the breast....

By Jelena Miolski, Mišela Raus, Milica Radusinović, Vera Zdravković