Non-steroidal anti-inflammatory drugs (NSAIDs) are ranked first among the world's effective anti-inflammatory and analgesic drugs with anticipated side effects. That is why the prevention of development of adverse reactions associated with NSAIDs, in particular, of those related to their ulcerogenicity, remains a serious global problem. Aims. To ch...

By Fedir Hladkykh

Vernix caseosa peritonitis (VCP) is a rare postpartum complication rarely recognized by clinicians despite an increased incidence of cesarean sections. A 23-year-old patient, who had not had any prior medical examination during pregnancy and with preterm premature rupture of the membranes (PPROM), gave birth by cesarean section. On the 4th day afte...

By Dejan Mihajlović, Novica Đoković, Leonida Vitković, Nenad Šulović, Milica Mijović

The aim of the study was to evaluate the association of mortality in acute pancreatitis with clinical and simple laboratory data received on the day of admission. In our retrospective study, the clinical and laboratory parameters of 99 patients with moderate and severe acute pancreatitis were analyzed. All patients were divided into two groups: dec...

By Tetiana Formanchuk, Volodymyr Shaprinskiy, Andrii Formanchuk

The clinical therapy of COVID-19 infection during pregnancy is still insufficient and limited. The current literature on COVID-19 infection during pregnancy and childbirth is summarized in this article, with a focus on maternal and neonatal outcomes. From June 1 to September 7, 2020, a systematic search of pertinent medical subject heading (MeSH) t...

By Nasrin Fazel, Sina Shahrooyan, Shohreh Shahrouyan

The key links in the etiology and pathogenesis of periodontal tissue diseases are the quantitative and qualitative changes in the composition of the microflora of the oral cavity, with the simultaneous deterioration of oral hygiene, and reduction of local and general immunity, which occurs more often in the presence of somatic diseases. The aim of ...

By Iryna Lisetska, Mikola Rozhko

Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020....

By Vahidreza Borhaninejad, Maryam Saber

This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...

By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye

Neutrophil-lymphocyte ratio (NLR) is one of the laboratory biomarkers used in clinical practice to predict severity and mortality of acute pancreatitis (AP), however, there is currently insufficient information about the changes of NLR in the dynamics in relationship with other clinical and laboratory data. To assess the relationship between NLR va...

By Tetiana Formanchuk, Hryhoriy Lapshyn, Mariya Pokidko, Andrii Formanchuk, Igor Vovchuk

The use of macronutrient and micronutrient foods is associated with the duration of sleep. This study aimed to determine the effect of zinc supplements on the sleep quality of older adults. The current parallel randomized clinical trial study was performed using a convenience sampling method. One hundred and fifty older adults who met the inclusion...

By Abolfazl Afzali, Mojarrad Mohandes, Shahrbanoo Goli, Hossein Bagheri, Seyedmohammad Mirhosseini, Hossein Ebrahimi

Quality of life is a state of complete physical, mental and social well-being. Due to the COVID-19 pandemic, which led to changes in the daily routine, there was a change in the psychosocial functioning of individuals. Given that laryngectomized patients belong to a vulnerable group that requires psychological support after surgery, specific epidem...

By Mirjana Petrović-Lazić, Snežana Babac, Ivana Ilić-Savić