Pseudothrombocytopenia induced by ethylenediaminetetraacetic acid is a rare phenomenon caused by autoantibodies against platelet membrane with overall prevalence of 0.1% in the general population. This phenomenon is an in vitro artifact and with different anticoagulant used, the patient had the physiological platelet count. This case is a report of...

By Dejan Dobrijević, Nataša Kaćanski-Rađenović, Jovanka Kolarović

Lung cancer is the leading cause of mortality from cancer across the world. In this study, the use of serum nucleolin (NCL) and nucleophosmin (NPM1) levels as a marker in the diagnosis, prognosis and treatment response evaluation in lung cancer was investigated. NCL and NPM1 levels of serum samples taken before chemotherapy and after 3-4 courses of...

By Gül Akın, Onur Esbah, Recep Eröz

Oxidative stress and resulting lipid peroxidation are involved in numerous pathological conditions. For this reason, the role of antioxidants attracts attention and the radical-scavenging capacity of many natural and synthetic supplements and drugs has been extensively evaluated. In the present study, seven N,N'-disubstituted benzimidazole-2-thione...

By Jelena Lazarević, Jelena Zvezdanović, Neda Anastassova, Anelia Mavrova, Denitsa Yancheva, Andrija Šmelcerović

Graves' disease is an autoimmune thyroid disease that is the most common cause of hyperthyroidism. Peripheral blood cell parameters such as neutrophils, lymphocytes, and platelets play a role in inflammation control. Several studies have proven that neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio and platelet-lymphocyte ratio are indicators ...

By Aksanur Gokce, Tulay Omma, Mustafa Çelikc, Işılay Taşkaldıran

Biologics (biopharmaceuticals) present new promising therapies for many diseases such as cancers, chronical inflammatory diseases and today's biggest challenge - COVID-19. Today, most biologics have been synthetized using modern methods of biotechnology, in particular DNA recombinant technology. Current pharmaceutical forms of protein/peptide bioph...

By Sanja Stanković, Marija Tasić-Kostov

The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 women (...

By Ljiljana Stošić, Dušica Stojanović, Konstansa Lazarević

FH is an autosomal dominant disease of lipid metabolism. Hypercholesterolemia, xanthomas, and death from early coronary artery disease (CAD) are common in this disease due to a mutation in the LDLR, Apo-B100 or PCSK9 genes. A 4-year-old male patient with a very rare heterozygous c.1730G > C (p.Trp577Ser) variation in exon 12 of the low-density l...

By Mustafa Doğan, Mehmet Koksal, Recep Eroz

The use of macronutrient and micronutrient foods is associated with the duration of sleep. This study aimed to determine the effect of zinc supplements on the sleep quality of older adults. The current parallel randomized clinical trial study was performed using a convenience sampling method. One hundred and fifty older adults who met the inclusion...

By Abolfazl Afzali, Mojarrad Mohandes, Shahrbanoo Goli, Hossein Bagheri, Seyedmohammad Mirhosseini, Hossein Ebrahimi

The chief aim of this study was monitoring of laboratory parameters of chronic kidney failure in elderly patients. All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect to ethical prin...

By Edhem Hasković, Harun Uzunalıć, Snežana Unčanin, Safija Herenda, Denis Hasković, Amina Selimović

Hypertension is a common disorder of old age, which could be prevented by medicinal herbs. The present study aimed to evaluate the effect of lavender extract on prehypertension in the retired population. This triple-blind clinical trial was conducted on 60 retired men and women who were divided into two groups of lavender extract and placebo using ...

By Mahboobeh Ahmadabadi, Fereshteh Ghorat, Raha Salehabadi, Sedigheh Rastaghi, Mostafa Rad