Clinical and simple laboratory data associated with fatal outcomes in patients with acute pancreatitis
The aim of the study was to evaluate the association of mortality in acute pancreatitis with clinical and simple laboratory data received on the day of admission. In our retrospective study, the clinical and laboratory parameters of 99 patients with moderate and severe acute pancreatitis were analyzed. All patients were divided into two groups: dec...
By Tetiana Formanchuk, Volodymyr Shaprinskiy, Andrii Formanchuk
Predictors of sexual dysfunction in HIV-infected men
The prevalence of sexual dysfunction in people infected with human immunodeficiency virus (HIV) is higher than in those without this infection. Sexual dysfunction in HIV-infected people is associated with adverse outcomes. This study aimed to investigate the predictors of sexual function in people infected with HIV. This cross-sectional study was d...
By Fatemeh Dadgar, Zeinab Moshfeghy, Roksana Janghorban, Marziyeh Doostfatemeh
Evaluation of the clinical and biochemical parameters of hospitalized COVID-19 patients: A retrospective, single-center study from Bosnia and Herzegovina
For the first time, we evaluated and presented the socio-demographic characteristics, clinical manifestations and laboratory findings of hospitalized coronavirus disease 2019 (COVID-19) patients from Canton Sarajevo, Bosnia and Herzegovina. This retrospective, single-centre study included 159 RT-PCR verified COVID-19 patients (92 mild/moderate; 67 ...
By Anela Šubo, Amela Dervišević, Zulejha Omerbašić, Muhamed Zeid, Selma Spahić, Almir Fajkić, Damir Suljević
Textural and sensory characterization of carbomeric gels with panthenol
The aim of this study was to evaluate the influence of the carbomer concentration (used as the gelling agent, in the range 0.5 - 2.0%) on textural and sensory characteristics of gels with 3% panthenol using sensory analysis as subjective and texture analysis as an objective assessment method. An active substance in the gels was panthenol, which als...
By Milica Martinović, Nenad Stojanović, Ivana Nešić
Administration of Cannabis causes alterations in monoamine oxidase B and serotonin receptor 2C gene expressions in Wistar rats
This study examined the probable effects of graded doses of Cannabis sativa (C. sativa) extract on the gene expressions of monoamine oxidase B and serotonin receptor 2C (HTR2C) in an attempt to correlate the duration of use with neurodegeneration tendencies in chronic marijuana users. Male Wistar rats weighing between 90 g ± 100 g were treat...
By Oluwatosin Dosumu, Oluwafemi Owolabi, Regina Ugbaja, Akinola Popoola, Solomon Rotimi, Odunayo Taiwo, Oluwafemi Ojo
Ultrastructural analysis of the surface changes on the nickel-titanium endodontic instruments after multiple use
One of the primary goals in endodontics is efficient cleaning and shaping of the root canal while maintaining its original configuration. Numerous studies highlight the advantage of using nickel-titanium instruments and the most important is their high flexibility and the ability to penetrate the curved canals. The aim of this study was to analyze ...
By Nenad Stošić, Jelena Popović, Marija Anđelković-Apostolović, Aleksandar Mitić, Marija Nikolić, Radomir Barac
Protein-protein interaction networks and protein-ligand docking: Contemporary insights and future perspectives
Traditional research means, such as in vitro and in vivo models, have consistently been used by scientists to test hypotheses in biochemistry. Computational (in silico) methods have been increasingly devised and applied to testing and hypothesis development in biochemistry over the last decade. The aim of in silico methods is to analyze the quantit...
By Aleksandar Velesinović, Goran Nikolić
Common mistakes in the choice of topical agents for emergency care of burns: Experimental study
The aim of the research was a histological study of the tissue structure of experimental animals with burns in dynamics using various topical agents after the injury. Experimental simulation of burn injuries was performed on 40 rats, which were divided into the main and control groups. Depending on the nature of care provided, the animals of the ma...
By Roman Chornopyshchuk, Vasyl Nagaichuk, Oleksandr Nazarchuk, Svetlana Sidorenko, Olena Urvan
Ertapenem neurotoxicity in patients with kidney damage: A case report
Ertapenem, a member of the carbapenem group of antibiotics, is a broad-spectrum antibiotic that is effective against multidrug-resistant gram-positive and gram-negative infections. In patients with acute or chronic kidney damage, one of the most serious side effects of ertapenem is neurotoxicity. Various clinical conditions such as seizures, halluc...
By Alper Alp, Yalkin Dalda
Effectiveness of Tocilizumab after switching from intravenous to subcutaneous formulation in patients with rheumatoid arthritis: A single-centre experience
Nowadays, the appropriate control of rheumatoid arthritis (RA) involves the absence of clinical disease activity, delaying joint destruction as long as possible and adequate quality of life of the affected. With currently available therapeutic modalities, this therapeutic goal can be achieved in a large number of patients. The aim of this research ...
By Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Ivana Aleksić, Jovana Cvetković