Neurological and psychiatric comorbidities in bullous pemphigoid
Bullous pemphigoid (BP) is an autoimmune skin disease that typically presents with severe itching and blistering, with or without eczematous and urticarial lesions. Patients with BP are at an increased risk of comorbid conditions, especially neurologic and psychiatric diseases. Several recent studies have found a link between BP and neurological di...
By Arsovska Mirceska, Katerina Damevska, Viktor Simeonovski, Andrija Jović, Danica Tiodorović
Cipargamin could inhibit human adenosine receptor A3 with higher binding affinity than Plasmodium falciparum P-type ATPase 4: An In silico study
This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...
By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye
An evaluation of the level of testosterone, DHEA and prolactin among Toxoplasma gondii infected and uninfected infertile couples attending to Fatima Al-Zahra infertility treatment center, Babol, Northern Iran
Toxoplasmosis modifies various hormones and cytokines in the infected hosts which may result in several disorders. This study was conducted to assess testosterone, DHEA, and prolactin concentration levels among Toxoplasma gondii infected and uninfected infertile couples. Blood samples were collected and sera were separated. The sera were analyzed f...
By Masomeh Bayani, Narges Kalantari, Sedigheh Esmailzadeh, Salman Ghaffari, Soleiman Mahjoub, Faezeh Ghofrani, Taraneh Ghaffari
Spectrophotometric method in comparative in vitro dissolution test of branded and generic ibuprofen tablets
The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...
By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov
Antimicrobial susceptibility pattern of oral viridans group Streptococci in children at risk of infective endocarditis
Infective endocarditis (IE) is an important clinical disease in children with a mortality rate of 11.6%. Prophylaxis with antibiotics is one of the most commonly used methods in children at risk of IE; therefore, the evaluation of antibiotic resistance seems necessary in view of its increasing trend. This study aimed to determine the antibiotic sus...
By Morva Moudi, Nilgoon Pasdar, Kazem Babazadeh, Zahra Shahandeh, Farahnaz Sadighian
Consultation length in ambulatory clinic of Belgrade Emergency Medical Service
The aim of the study was to analyze and compare consultation lengths in Emergency Medical Service (EMS) Belgrade ambulatory clinic which relates to patient age, gender, existing diagnoses and prescribed treatment (therapy or referral to another healthcare institution). We analyzed the data from the electronic database on consultation lengths from o...
By Slavoljub Živanović, Miloranka Petrov-Kiurski
Compilation and testing the reliability of questionnaires about the fear of blood extraction (venipuncture) among students of Medical Faculty of Kragujevac
It is of particular importance to use validated questionnaires to remove fear of needles and blood collection, as this public health problem has been observed in a large number of patients and may inadequately affect medical healthcare. The aim of the study was to conduct a research on the reliability of the questionnaire on the fear of blood sampl...
By Suzana Milutinović, Ana Stanković, Sunčica Ivanović, Sanja Trgovčević, Tatjana Kilibarda
Epidemiological and etiological aspects of dental caries development
The infectious factor is etiological in the caries development. Early colonization of S. mutans is considered as a key point; another important caries-associated microorganism is Lactobacillus, which colonizes carious lesions later. Ecological shifts in the dental plaques against the background of weakened local immunity increase their cariogenicit...
By Loban' Andriivna, Faustova Oleksiivna, Chereda Volodymyrivna, Ananieva Mykolaivna
Review on home care recommendations for patients with suspected COVID-19 presenting with mild symptoms
Caring for COVID-19 patients at home is a global challenge. This study aimed to review recommendations put forward on home care for patients with suspected COVID-19 presenting with mild clinical features. This is a review of the scientific literature covering COVID-19 and home care from the medical electronic databases such as PubMed, ProQuest, Goo...
By Javad Dehghannezhad, Vahid Zamanzadeh, Damanabad Heydarpoor, Hadi Hassankhani, Malcolm Boyle, Abbas Dadashzadeh
A complex rare presentation of rice tablet poisoning: A case report
Aluminum phosphide, known as "rice tablet" (RT), is a common cause of suicide in adult women in Iran, with a high rate of lethal outcome. We report a patient with RT toxicity, with a complex syndrome of hepatic failure, renal failure, Brugada electrocardiography (ECG) patterns, and pleuropericardial effusion. The patient received conventional manag...
By Feridoun Sabzi, Aghigh Heydari, Reza Moghaddam, Mohammad Rouzbahani, Atefeh Asadmobini