Situs inversus totalis represents a rare autosomal recessive morphological anomaly of the internal viscera, equally affecting both genders. The genetic defect occurs in the 2nd week of embryonic life, when a 270-degree clockwise rotation of the primitive digestive tube occurs. The incidence of calculosis of gallbladder in patients with situs invers...

By Radomir Gelevski, Gjorgji Jota, Lazar Todorović, Gjorgji Trajkovski, Vladimir Joksimović, Bojan Trenčić

The prevalence of diabetes mellitus (DM) is increasing in many countries. A lower prevalence of DM type 2 and other glucose metabolism disorders was observed in populations consuming larger amounts of n-3 polyunsaturated fatty acids, existing mainly in fish. Docosahexaenoic acid (DHA) is an important signaling molecule required for the central nerv...

By Sahar Mahmoud, Yasmin Latif, Hisham Orban, Amr Ibrahim, Jihan Hussein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus strain that caused coronavirus disease 2019 (COVID-19). This novel coronavirus is an emerging global health threat. It caused approximately 140 million confirmed cases, with about 3 million deaths worldwide until April 18, 2021. Although there are two approved medications for...

By Zeinab Afshar, Arefeh Babazadeh, Mostafa Javanian, Mohammad Barary, Vasigala Rekha, Soheil Ebrahimpour

In this study, the nutrient contents of "Kati", a fermented cereal-based food, was revealed and antifungal activity of bacteriocin producing lactic acid bacteria (LAB) from "Kati" was assessed against aflatoxigenic Aspergillus flavus (A. flavus). The protein content (9.29%) of "Kati" was higher than (p < 0.05) wet milled-fermented sorghum (6.17%...

By Gabriel Oladimeji, Ogidi Olusola, Olaniyi Oladiti, Bamidele Akinyele

Acne vulgaris is a chronic dermatological disease that affects the pilosebaceous unit; androgens play an important role in its pathogenesis. Acne therapy can be either systemic or topical, usual in the treatment of mild and moderate forms of acne. Spironolactone (SP) is an anti-androgen drug with potential to reduce the sebum secretion; in order to...

By Dušan Ilić, Maja Cvetković, Marija Tasić-Kostov

Traditional research means, such as in vitro and in vivo models, have consistently been used by scientists to test hypotheses in biochemistry. Computational (in silico) methods have been increasingly devised and applied to testing and hypothesis development in biochemistry over the last decade. The aim of in silico methods is to analyze the quantit...

By Aleksandar Velesinović, Goran Nikolić

The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...

By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov

Infective endocarditis (IE) is an important clinical disease in children with a mortality rate of 11.6%. Prophylaxis with antibiotics is one of the most commonly used methods in children at risk of IE; therefore, the evaluation of antibiotic resistance seems necessary in view of its increasing trend. This study aimed to determine the antibiotic sus...

By Morva Moudi, Nilgoon Pasdar, Kazem Babazadeh, Zahra Shahandeh, Farahnaz Sadighian

Ballet is a professional activity that places risky physical and psycho-emotional demands on the human body. The goal of this study was to evaluate health-related problems among ballet dancers. Within the qualitative study, in-depth interviews were conducted with ballet dancers at the State Ballet of Georgia. Participants' mean age was 23.4 &plusmn...

By Tengiz Verulava, Ketevan Tvalavadze, Revaz Jorbenadze

Asthma and allergic disorders can affect the outcome of pregnancy. Asthma and allergies are common comorbidities during pregnancy and exacerbations are the major clinical problem. Results are not consistent between studies .Therefore, the aim of this study was to determine the frequency of asthma and allergic disease during pregnancy. This prospect...

By Nasrin Fazel, Asghar Kazemzadeh, Mojtaba Abdizadeh, Erika Jensem-Jarolim, Shohreh Shahrouyan, Sina Shahrooyan