This study examined the probable effects of graded doses of Cannabis sativa (C. sativa) extract on the gene expressions of monoamine oxidase B and serotonin receptor 2C (HTR2C) in an attempt to correlate the duration of use with neurodegeneration tendencies in chronic marijuana users. Male Wistar rats weighing between 90 g ± 100 g were treat...

By Oluwatosin Dosumu, Oluwafemi Owolabi, Regina Ugbaja, Akinola Popoola, Solomon Rotimi, Odunayo Taiwo, Oluwafemi Ojo

One of the primary goals in endodontics is efficient cleaning and shaping of the root canal while maintaining its original configuration. Numerous studies highlight the advantage of using nickel-titanium instruments and the most important is their high flexibility and the ability to penetrate the curved canals. The aim of this study was to analyze ...

By Nenad Stošić, Jelena Popović, Marija Anđelković-Apostolović, Aleksandar Mitić, Marija Nikolić, Radomir Barac

Traditional research means, such as in vitro and in vivo models, have consistently been used by scientists to test hypotheses in biochemistry. Computational (in silico) methods have been increasingly devised and applied to testing and hypothesis development in biochemistry over the last decade. The aim of in silico methods is to analyze the quantit...

By Aleksandar Velesinović, Goran Nikolić

Ballet is a professional activity that places risky physical and psycho-emotional demands on the human body. The goal of this study was to evaluate health-related problems among ballet dancers. Within the qualitative study, in-depth interviews were conducted with ballet dancers at the State Ballet of Georgia. Participants' mean age was 23.4 &plusmn...

By Tengiz Verulava, Ketevan Tvalavadze, Revaz Jorbenadze

The aim of the research was a histological study of the tissue structure of experimental animals with burns in dynamics using various topical agents after the injury. Experimental simulation of burn injuries was performed on 40 rats, which were divided into the main and control groups. Depending on the nature of care provided, the animals of the ma...

By Roman Chornopyshchuk, Vasyl Nagaichuk, Oleksandr Nazarchuk, Svetlana Sidorenko, Olena Urvan

Ertapenem, a member of the carbapenem group of antibiotics, is a broad-spectrum antibiotic that is effective against multidrug-resistant gram-positive and gram-negative infections. In patients with acute or chronic kidney damage, one of the most serious side effects of ertapenem is neurotoxicity. Various clinical conditions such as seizures, halluc...

By Alper Alp, Yalkin Dalda

Nowadays, the appropriate control of rheumatoid arthritis (RA) involves the absence of clinical disease activity, delaying joint destruction as long as possible and adequate quality of life of the affected. With currently available therapeutic modalities, this therapeutic goal can be achieved in a large number of patients. The aim of this research ...

By Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Ivana Aleksić, Jovana Cvetković

The aim of the study was to investigate the microscopic renal changes resulting from the concurrent administration of chloroquine and ethanol, with inadequate dietary protein using rats. Sixty-four rats were randomly distributed into eight groups of eight rats each: control groups on normal protein (NPC) or low protein diet (LPC); chloroquine treat...

By Abdurrahman Abdulkadir, Ejikeme Mbajiorgu

Pulmonary arterial hypertension (PAH), which occurs in about 15% of patients with systemic sclerosis (SSc), is a progressive vasculopathy and despite modern therapeutic options is still one of the leading causes of death in these patients. We presented a patient diagnosed with the overlap syndrome (systemic sclerosis and rheumatoid arthritis) with ...

By Ivana Aleksić, Sandra Šarić, Bojan Ilić, Sonja Stojanović, Marina Deljanin-Ilić

Sexual dysfunction is more common among the people with human immunodeficiency virus (HIV) infection than in those without it. The sexual dysfunction in HIV-infected people is associated with adverse outcomes such as reduced quality of life, unprotected sexual activities, and reduced adherence to highly active antiretroviral therapy. Therefore, the...

By Zeinab Moshfeghy, Fatemeh Dadgar, Roksana Janghorban, Tahereh Poordast