This present research work was designed to investigate the potential chemopreventive effects of Annona Muricata on cadmium-induced hepatotoxicity and oxidative neuronal damage in Wistar albino rats. In this study, twenty-eight (28) Wistar albino rats were randomized into four groups, with seven rats each. Group A served as the control and provided ...

By Johnson Oladele, Omowumi Adewale, Olu Oyewole, Mistura Salami, Ganiyat Owoade, Oyedotun Oyeleke

"Off-label drug use" refers to the prescription of medications, with reference to indications, dosage, dosage form, patient group or route of administration, which are officially unapproved. Recently, new indications for some drugs have emerged and few of them are being used off-label to treat topically a variety of dermatological conditions. Off-l...

By Marija Tasić-Kostov, Dušan Ilić

Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-ar...

By Ivana Nešić, Vesna Savić, Ana Kolarević

Löfgren’s syndrome is an acute form of sarcoidosis characterized by fever, erythema nodosum (EN), bilateral hilar lymphadenopathy (BHL), and polyarthritis. This syndrome is a self-limiting disease. A 45-year-old woman was admitted to our hospital complaining of fever, visual blurring, and arthralgia. A chest radiograph showed bilateral h...

By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Afshar Mohseni, Mehran Shokri, Arefeh Babazadeh

Pelvis is a strong bony-ligamentous structure containing many organs, vessels and nerves. Three forces or a combination of those forces produce pelvic fractures. The main causes of pelvic fractures are traffic accidents and falls from height. Biomechanically pelvic ring can be stable or unstable. Biomechanically unstable pelvic ring after the injur...

By Saša Milenković, Milan Mitković

Antioxidant properties of 2-[2-imino-5-nitro-3-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-benzimidazol1-yl]-1-phenylethanone (compound 1) and 2-(4-fluorobenzylidene)-6-(phenylcarbonyl)[1,3]thiazolo[3,2a]benzimidazol-3(2H)-one (compound 2) were evaluated in vitro. Compounds 1 and 2 did not show significant radical scavenging activity. It has been suggeste...

By Katarina Tomović, Jelena Mrmošanin, Denitsa Yancheva, Anelia Mavrova, Andrija Šmelcerović

The aim of the study was to determine the correlation between depression levels, oral health, oral health habits and subjective feelings in the region of the mouth and teeth in senior medical students. A total of 103 students at the final study year at the Faculty of Medical Science, University of Kragujevac, participated in the research. Two types...

By Miloš Stepović, Zlata Rajković, Dailbor Stajić, Marija Sekulić, Milena Maričić, Nela Đonović

Peripheral T/NK–cell lymphomas (PTCL) are rare, bizarre, and extremely diverse cancers. The disease is prone to relapse with a high level of chemorefractoriness leading to a poor outcome. Almost 70% of patients will experience relapse, with a median 5–year overall survival (OS) in approximately 30%. Upfront management of PTCL has been e...

By Ivan Petković, Aleksandar Popović, Miljana Džunić, Ivica Pejčić

Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...

By Nimet Kalkan, Mehmet Tezcan

Normal development is one of the reliable criteria for the assessment of children's health status. Perinatal events affect the future development of children. Nevertheless, there are different views on the impact of events in the perinatal period on child development. The aim of this study was to determine the relationship between perinatal period ...

By Masoumeh Kaviani, Zhaleh Ranjbaran, Roksana Janghorban