Malocclusions are common oral health issues that require precise assessment of severity and the need for orthodontic treatment. The Index of Orthodontic Treatment Need (IOTN) is a reliable tool for objectively evaluating the necessity of orthodontic therapy. This study aimed to determine the need for orthodontic treatment among children and adolesc...

By Andjelka Cvijić, Iva Jakovljević, Aleksandra Arnaut, Roberta Marković, Tatjana Čutović

Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...

By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić

Nizon-Isidor syndrome (NIZIDS) is a rare genetic disorder associated with mutations in the MED12L gene and is usually characterized by a distinctive facial appearance, neurodevelopmental delay, autism spectrum disorders (ASD), and chronic gastrointestinal symptoms (GIS). In this case report, we emphasize the importance of early evaluation of geneti...

By Mehmet Semih Demirtaş, Yakup Köylü

Older edentulous adults often rely on mucosa-supported complete dentures (CDs) due to limitations that preclude implant therapy. Although an adequate retention of maxillary CD is essential for functional efficiency, compression of the palatal mucosa during impression making may compromise palatal mucosal microcirculation during denture wear. T...

By Petar Tekić, Stefan Vulović, Marija Milić, Marko Igić, Milena Kostić, Aleksandra Popovac, Ivica Stančić, Aleksandra Milić Lemić

Loeffler's endocarditis (LE) is a rare form of inflammatory cardiomyopathy. The condition arises from diffuse eosinophilic infiltration of the endomyocardium, followed by eosinophil degranulation and progressive tissue fibrosis. The aim of this case report is to present a rare form of restrictive cardiomyopathy, LE, in a young female patient, and t...

By Milica Kotur, Nikola Pantić, Lenka Grujičić, Isidora Grozdić-Milojević, Dragana Šobić-Šaranović, Vera Artiko, Strahinja Odalović

Diabetes mellitus is one of the most common chronic diseases in childhood. The aim of this study was to evaluate the oral health of children with type 1 diabetes in relation to the level of glycemic control. 87 children aged 10 to 15 participated in the study, divided into two groups according to the value of glycosylated hemoglobin (HbA1c): 34 chi...

By Mirjana Djuričković, Aleksa Djuričković

Aluminium is a metal that disrupts the pro-oxidant and antioxidant balance in tissues, leading to biochemical dysfunction. The present study evaluated the protective effect of rutin on aluminium chloride (AlCl3)-induced hepatorenal toxicity in Wistar rats. Twenty male Wistar rats were divided into four groups: Group 1-control, Group 2 received AlCl...

By Olu Israel Oyewole, Ayoola Mary Bukoye

COVID-19 infection may exacerbate glycemia and lead to metabolic problems in people with diabetes. Emerging data suggest that diabetes may also develop during coronavirus infection in individuals with no prior history of the disease. This study aimed to analyze the prevalence of new-onset hyperglycemia and diabetes mellitus (nDM) in COVID-19 patien...

By Samar Maher Yassin, Zaid Al-Attar

Quality of sleep (QoS) in the third-trimester of pregnancy has been suggested as a potential risk factor for the onset of non-psychotic postpartum depression (NPPD). The aim of the paper was to investigate whether the quality of sleep in the third-trimester of pregnancy is a risk factor for nonpsychotic postpartum depression (NPPD) in women without...

By Jelena Stojanov, Olivera Žikić, Miodrag Stanković

Cystic changes of the spleen are one of the rare clinical entities in the pediatric population. The paper presents a partial splenectomy in children performed by open approach as a safe surgical treatment of giant epithelial splenic cysts. Two cases of giant epithelial cysts of the spleen in children are presented. Medical documents and data referr...

By Maja Zečević, Zoran Marjanović, Dragoljub Živanović, Goran Janković, Nikola Živković, Živojin Spasić, Strahinja Konstantinović