Pelvis is a strong bony-ligamentous structure containing many organs, vessels and nerves. Three forces or a combination of those forces produce pelvic fractures. The main causes of pelvic fractures are traffic accidents and falls from height. Biomechanically pelvic ring can be stable or unstable. Biomechanically unstable pelvic ring after the injur...

By Saša Milenković, Milan Mitković

Remodeling of the myocardium in patients with primary aldosteronism (PA) is mediated by the presence of mineralocorticoid receptors on the myocytes and fibroblasts. The goal of this study was to analyze the effect of arterial hypertension and metabolic disorders on the cardiovascular system in patients with PA. We recruited 54 patients with PA, 32 ...

By Andryi Nykonenko, Iryna Zubryk, Oleksandr Podluzhnyi, Olrksandr Molodan, Sergii Bukhtii, Oleksandr Nykonenko

Peripheral T/NK–cell lymphomas (PTCL) are rare, bizarre, and extremely diverse cancers. The disease is prone to relapse with a high level of chemorefractoriness leading to a poor outcome. Almost 70% of patients will experience relapse, with a median 5–year overall survival (OS) in approximately 30%. Upfront management of PTCL has been e...

By Ivan Petković, Aleksandar Popović, Miljana Džunić, Ivica Pejčić

Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...

By Nimet Kalkan, Mehmet Tezcan

Sigmoid sinus septic thrombosis is an infrequent complaint that may lead to extensive morbidity and mortality. We report a case with septic thrombosis of the sigmoid sinus caused by chronic mastoiditis and otitis media. A 29-year-old male presented with a 14-day history of tinnitus and true vertigo with a gradually developing swelling on the right ...

By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Zeinab Afshar, Arefeh Babazadeh

Normal development is one of the reliable criteria for the assessment of children's health status. Perinatal events affect the future development of children. Nevertheless, there are different views on the impact of events in the perinatal period on child development. The aim of this study was to determine the relationship between perinatal period ...

By Masoumeh Kaviani, Zhaleh Ranjbaran, Roksana Janghorban

Considerable share of patients admitted to the intensive care unit, during the current Covid-19 pandemic, are obese. Obesity is associated with chronic low-grade inflammation, higher endothelial injury, higher levels of angiotensinogen II and increased expression of angiotensin-converting enzyme 2 receptors in the adipose tissue. These alterations ...

By Vesna Marjanović

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

Genetic counselling is a complex process that helps people to understand and adopt medical, psychological and genetic aspects of the disease and enable them to make an appropriate decision. In this framework, we revisited all the existing models for decision-making and suggested their use in the process of genetic counselling, which may lead to mor...

By Marija Lević, Dušanka Krajnović, Valentina Marinković

Anxiety is an inborn emotional and cognitive reaction that enables humans to cope with everyday situations, however, it can be pathological as well. Although Spielberger’s State-Trait Anxiety Inventory (STAI) scales are most frequently used to study the presence/absence of anxiety, there is a lack of empirical studies in Serbian healthy and/o...

By Nikola Stojanović, Pavle Ranđelović, Gordana Nikolić, Nenad Stojiljković, Sonja Ilić, Bogdan Stoiljković, Niko Radulović