Comparison of the effects of heparin 1000 and 5000 units on arterial blood gases
Analysis of arterial blood gases is necessary for managing the respiratory and metabolic parameters of patients in the intensive care unit. The aim of this study was to compare the effects of heparin 1000 and heparin 5000 units on arterial blood gases in patients admitted to the intensive care unit. This study was a triple-blinded clinical trial. A...
By Reza Borabadi, Mostafa Rad, Mohammad Rakhshani, Mojtaba Rad
Annona Muricata protects against cadmium-mediated oxidative damage in the brain and liver of rats
This present research work was designed to investigate the potential chemopreventive effects of Annona Muricata on cadmium-induced hepatotoxicity and oxidative neuronal damage in Wistar albino rats. In this study, twenty-eight (28) Wistar albino rats were randomized into four groups, with seven rats each. Group A served as the control and provided ...
By Johnson Oladele, Omowumi Adewale, Olu Oyewole, Mistura Salami, Ganiyat Owoade, Oyedotun Oyeleke
A new approach to maggot therapy for healing of diabetic foot ulcers
The use of maggot therapy (MT) is proving effective in the treatment of complicated diabetic foot ulcers (DFUs). Most of the previous studies have focused on the comparison of MT and routine treatment approaches for the management of DFUs. The aim of this study was to add MT to routine treatment line of DFUs as a new approach. In this study, the pr...
By Omid Dehghan, Tabaie Mehdi, Javad Rafinejad, Mehrangiz Toutonnchy, Amir Tiyuri, Kamran Akbarzadeh, Haghi Motevalli
Off-label prescriptions in dermatology: Challenges of new routes of administration for certain old drugs
"Off-label drug use" refers to the prescription of medications, with reference to indications, dosage, dosage form, patient group or route of administration, which are officially unapproved. Recently, new indications for some drugs have emerged and few of them are being used off-label to treat topically a variety of dermatological conditions. Off-l...
By Marija Tasić-Kostov, Dušan Ilić
Investigation of efficacy of anti-aging liposomal intimate gel: An in vivo long-term study
Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-ar...
By Ivana Nešić, Vesna Savić, Ana Kolarević
Löfgren's syndrome with splenic involvement: A case report
Löfgren’s syndrome is an acute form of sarcoidosis characterized by fever, erythema nodosum (EN), bilateral hilar lymphadenopathy (BHL), and polyarthritis. This syndrome is a self-limiting disease. A 45-year-old woman was admitted to our hospital complaining of fever, visual blurring, and arthralgia. A chest radiograph showed bilateral h...
By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Afshar Mohseni, Mehran Shokri, Arefeh Babazadeh
In vitro antioxidant properties of 2-imino-benzimidazole and 1,3-thiazolo[3,2-a]benzimidazolone derivatives
Antioxidant properties of 2-[2-imino-5-nitro-3-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-benzimidazol1-yl]-1-phenylethanone (compound 1) and 2-(4-fluorobenzylidene)-6-(phenylcarbonyl)[1,3]thiazolo[3,2a]benzimidazol-3(2H)-one (compound 2) were evaluated in vitro. Compounds 1 and 2 did not show significant radical scavenging activity. It has been suggeste...
By Katarina Tomović, Jelena Mrmošanin, Denitsa Yancheva, Anelia Mavrova, Andrija Šmelcerović
Association between depression levels and self-perceived oral health among medical students
The aim of the study was to determine the correlation between depression levels, oral health, oral health habits and subjective feelings in the region of the mouth and teeth in senior medical students. A total of 103 students at the final study year at the Faculty of Medical Science, University of Kragujevac, participated in the research. Two types...
By Miloš Stepović, Zlata Rajković, Dailbor Stajić, Marija Sekulić, Milena Maričić, Nela Đonović
Diet may be the most relevant feature for the success of urate lowering therapy in gout
Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...
By Nimet Kalkan, Mehmet Tezcan
Relationship between perinatal period problems and developmental delay in children aged 4-24 months
Normal development is one of the reliable criteria for the assessment of children's health status. Perinatal events affect the future development of children. Nevertheless, there are different views on the impact of events in the perinatal period on child development. The aim of this study was to determine the relationship between perinatal period ...
By Masoumeh Kaviani, Zhaleh Ranjbaran, Roksana Janghorban