Ivermectin Protects against Monosodium Glutamate-Induced Excitotoxicity in the Rat
Summary Monosodium glutamate (MSG), an established excitotoxic food additive, has been found to induce oxidative stress in all tissues. To examine the protective effects of ivermectin on MSG-induced excitotoxicity, 28 male albino rats were randomized into four groups. Group 1, the control, received 1 ml of oral distilled water, group 2 was administ...
By Rotimi O. Arise, Abimbola K. Arise, Oluwole I. Oyewole, Sylvia O. Malomo
Erythropoietin Resistance in Hemodialysis Patients
Summary Anemia is defined as blood hemoglobin concentration of less than 120 g/l in women and less than 130 g/l in men. The main cause of the development of anemia in patients treated with regular hemodialysis is the lack of endogenous erythropoietin, and its main clinical consequences are: progressive decline in residual renal function, developmen...
By Saša Jacović, Milena Jovanović, Nedim Hamzagić, Radiša Pavlović, Dejan Petrović
Predictors of potential drug-drug interactions in patients at intensive care unit
Drug-drug interactions (DDIs) with serious adverse consequences for patients at intensive care unit (ICU) occur with the prevalence of 5.3%. The aim of our study was to reveal the risk factors for potential DDIs among the ICU patients. This retrospective cohort analysis took place in the ICU of the Clinical Center Podgorica, Montenegro, between Jun...
By Ivana Iličković, Vesna Orlandić-Čejović, Sanja Tanasković, Slobodan Janković
Erratum
ERRATUM The article entitled “Evaluation of Prognostic Factors Involved in Seroma Formation after Radical Surgery for Breast Cancer“, authored by: Miodrag Djordjević , Toplica Bojić , Lidija Djordjević , Dragana Budjevac , Nebojša Djordjević, Nebojša Ignjatović, Ivan Pešić, Ana Cvetanović , Mladjan Golubović , Jo...
The impact of disease activity in patients with rheumatoid arthritis on metabolic syndrome and cardiovascular risk assessment
Patients with rheumatoid arthritis (RA) have a 1.5 times higher cardiovascular disease mortality compared to the general population, while the life expectancy of these patients is 5-10 years shorter compared to the general population. In RA patients, all stages of atherogenic process are accelerated. Systemic inflammation underlying RA is an indepe...
By Ivana Aleksić, Sonja Stojanović, Ivan Tasić, Bojana Stamenković
Adjustment and Its Association with Demographic and Clinical Factors among Iranian Population with Type 2 Diabetes Mellitus: The First Native Diabetes Adjustment Assessment Scale
The prevalence of diabetes is increasing worldwide. Middle Eastern countries will be confronting an im-mense increase in the number of diabetes mellitus cases by 2030. Living with diabetes mellitus has been characterized as a dynamic individual transitive adjustment, based on restructuring of the illness perceived experience and management of the s...
By Parviz Sadeghi, Hossein Namdar Areshtanab, Rasoul Zarrin, Hossein Ebrahimi, Reza Sabanloei
Using Team-Based Learning to Teach Evidence-Based Medicine to First-Year Residents
Summary Team-based learning (TBL) is a well-established instructional strategy that provides students with the chance to apply conceptual knowledge through a series of actions, including pre-class, individual, team class activity, and immediate feedback. The purpose of the present study was to introduce a course of teaching the evidence-based medic...
By Mandana Akbarinejad Mousavi, Mitra Amini, Somayeh Delavari, Ali Seifi
Reliability of microbiological tests in the diagnosis of Clostridium difficile infection
The aim of the study was to analyze the characteristics {sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and credibility} of tests for microbiological diagnosis of infections caused by Clostridium (C. difficile). The research was done at the Public Health InstituteNiš, the Center for Microbiology du...
By Predrag Stojanović, Niko Radulović, Branislava Kocić, Marina Dinić, Biljana Miljković-Selimović, Kristina Stojanović
Traumatic Intrahepatic Biloma – A Rare Entity Mimicking Neoplasm of the Liver: A Case Report
Summary Bilomas represent large collections of bile, produced due to a rupture of bile ducts. Most frequently, they are located in the perihepatic tissues, rarely intrahepatic ones. Usually, bile ducts rupture is caused by trauma, spontaneous or iatrogenic, or some underlying disease. The majority of bilomas cases are treated by means of drainage p...
By Aleksandra Radovanović, Miljan Krstić, Jasmina Gligorijević, Aleksandra Veličkov, Marko Stojanović
Chemo-herbal potentials of fractionalized extract of Mimosa pudica in cadmium-induced hepatocellular tumor with associated Alpha-fetoprotein and gamma-glutamyl transferase elevation
The plant Mimosa pudica (M. pudica) has been reported by researchers as an anti-inflammatory herb, amongst other properties, but its use as an anticancer herb is still sketchy. This study was aimed at evaluating the n-hexane, butanol and aqueous fractions of M. pudica leaf extract as a chemo-herbal therapy in cadmium-induced hepatocellular tumor. F...
By Monday Felix, Ekiokakpo Patience, Chukwuma Ferdinand, Obari Osaro