Comparison of the effects of heparin 1000 and 5000 units on arterial blood gases
Analysis of arterial blood gases is necessary for managing the respiratory and metabolic parameters of patients in the intensive care unit. The aim of this study was to compare the effects of heparin 1000 and heparin 5000 units on arterial blood gases in patients admitted to the intensive care unit. This study was a triple-blinded clinical trial. A...
By Reza Borabadi, Mostafa Rad, Mohammad Rakhshani, Mojtaba Rad
Annona Muricata protects against cadmium-mediated oxidative damage in the brain and liver of rats
This present research work was designed to investigate the potential chemopreventive effects of Annona Muricata on cadmium-induced hepatotoxicity and oxidative neuronal damage in Wistar albino rats. In this study, twenty-eight (28) Wistar albino rats were randomized into four groups, with seven rats each. Group A served as the control and provided ...
By Johnson Oladele, Omowumi Adewale, Olu Oyewole, Mistura Salami, Ganiyat Owoade, Oyedotun Oyeleke
Off-label prescriptions in dermatology: Challenges of new routes of administration for certain old drugs
"Off-label drug use" refers to the prescription of medications, with reference to indications, dosage, dosage form, patient group or route of administration, which are officially unapproved. Recently, new indications for some drugs have emerged and few of them are being used off-label to treat topically a variety of dermatological conditions. Off-l...
By Marija Tasić-Kostov, Dušan Ilić
Investigation of efficacy of anti-aging liposomal intimate gel: An in vivo long-term study
Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-ar...
By Ivana Nešić, Vesna Savić, Ana Kolarević
Löfgren's syndrome with splenic involvement: A case report
Löfgren’s syndrome is an acute form of sarcoidosis characterized by fever, erythema nodosum (EN), bilateral hilar lymphadenopathy (BHL), and polyarthritis. This syndrome is a self-limiting disease. A 45-year-old woman was admitted to our hospital complaining of fever, visual blurring, and arthralgia. A chest radiograph showed bilateral h...
By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Afshar Mohseni, Mehran Shokri, Arefeh Babazadeh
In vitro antioxidant properties of 2-imino-benzimidazole and 1,3-thiazolo[3,2-a]benzimidazolone derivatives
Antioxidant properties of 2-[2-imino-5-nitro-3-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-benzimidazol1-yl]-1-phenylethanone (compound 1) and 2-(4-fluorobenzylidene)-6-(phenylcarbonyl)[1,3]thiazolo[3,2a]benzimidazol-3(2H)-one (compound 2) were evaluated in vitro. Compounds 1 and 2 did not show significant radical scavenging activity. It has been suggeste...
By Katarina Tomović, Jelena Mrmošanin, Denitsa Yancheva, Anelia Mavrova, Andrija Šmelcerović
Association between depression levels and self-perceived oral health among medical students
The aim of the study was to determine the correlation between depression levels, oral health, oral health habits and subjective feelings in the region of the mouth and teeth in senior medical students. A total of 103 students at the final study year at the Faculty of Medical Science, University of Kragujevac, participated in the research. Two types...
By Miloš Stepović, Zlata Rajković, Dailbor Stajić, Marija Sekulić, Milena Maričić, Nela Đonović
Position-related somatotype of elite female handball players
Anthropometric characteristics and motor abilities are the most influential factors for the achievement of top sports results. The sample of participants consisted of elite female handball players (n = 19, mean age: 27.67 years ± 6 months), the members of the Serbian senior national team. In this research, their body constitution, i.e. their...
By Emilija Petković, Saša Bubanj, Kristina Marković, Miodrag Kocić, Daniel Stanković
Therapy of peripartum mental disorders
During the peripartum period, women are at a greater risk of developing a mental disorder or experiencing an exacerbation of the pre-existing mental disorders. Therapeutic interventions are based primarily on psychotherapy, but if the symptoms are severe and pose a risk to the mother and the child, then the use of drugs, hospitalization or electroc...
By Miodrag Stanković, Jelena Stojanov, Jovana Antonijević
Impact of exercise training on dipeptidyl peptidase 4 and insulin-like growth factor binding protein 1 in patients with coronary artery disease: Relationship to nitric oxide response
Dipeptidyl peptidase 4 (DPP4) is a proteolytic enzyme, involved in a wide range of different cellular functions and expressed on the surface of most cell types, including the endothelium. The circulating level of insulin-like growth factor (IGF) binding protein 1(BP1) is associated with insulin resistance and diabetes, but it also affects the progn...
By Dejan Simonović, Marina Deljanin-Ilić, Gordana Kocić, Gordana Lazarević, Branka Đorđević, Sandra Šarić, Sanja Stojanović, Stevan Ilić