The aim of the research was to investigate prognostic factors in patients with resected colorectal liver metastases (CLMs) after biological and chemotherapy, which made initially unresectable disease suitable for resection. Sixty-six patients with resected CLMs, operated after induction bio-chemotherapy with bevacizumab + FOLFOX4, treated at the Cl...

By Miljana Džunić, Ivan Petković, Ana Cvetanović, Ivica Pejčić, Svetislav Vrbić, Saša Dinić

Poor oral hygiene and diseases of the teeth and oral tissues can affect all aspects of patients' lives. The aim of the study was to determine the subjective assessment of oral and general health and their impact on the quality of life in elderly patients. The research included 46 patients, geriatric center users, who were asked questions from a thr...

By Milena Kostić, Marko Igić, Ana Pejčić

Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

As a complex and multidimensional problem, the occupational burnout causes absence, dissatisfaction, badtemper, physical and emotional exhaustion and displacement. This study aimed to investigate the levels of occupational burnout and its components in Mazandaran's hospitals by the kind of their ownership. This descriptive-analytical study was cond...

By Ghahraman Mahmoudi, Jahani Ali, Masoomeh Abdi, Sedigheh Solimanian, Nikbakht Ali, Soheil Ebrahimpour

The maternal mortality rate (MMR) often reflects the development status of one country. This study calculates the incidence rate of maternal mortality and examines the related risk factors in Fars Province, located in South of Iran. Using the surveillance system of Shiraz University of Medical Sciences, we reviewed all childbirth records from 2002 ...

By Alireza Mirahmadizadeh, Fariba Moradi, Elham Hesami, Ahmad Maghsoudi, Amin Mirahmadizadeh, Ali Seifi, Mahsa Kiani, Mohsen Moghadami

The purpose of the study was to investigate the effects of Exendin-4 on polycystic ovary syndrome (PCOS) in rats in chronic mild stress medium. For establishing the PCOS model, dehydroepiandrosterone (DHEA) (6mg/100g) in 0.2ml sesame oil was injected subcutaneously to 21-day old rats (n = 67). In addition, 0.2ml sesame oil was injected subcutaneous...

By Burcu Köksal, Sedat Yildiz, Tugba Ozgöcer, Azibe Yildiz, Nigar Vardi, Özlem Barutcu

Pathological biomineralization can be found in some gallbladder (GB) diseases such as chronic calculous cholecystitis (CCCh), gallbladder cancer (GBC) and porcelain gallbladder (PGB). The aim of the work was to analyze the morphology of pathological biomineralization in GB tissue in CCCh, GBC and PGB. Five cases of PGB, 10 samples of CCCh and 5 cas...

By Roman Moskalenko, Sergiy Danilchenko, Artem Piddubnyi, Oleksandr Kravets, Inna Chorna, Olena Kolomiets, Anatolii Romaniuk

Summary Bilomas represent large collections of bile, produced due to a rupture of bile ducts. Most frequently, they are located in the perihepatic tissues, rarely intrahepatic ones. Usually, bile ducts rupture is caused by trauma, spontaneous or iatrogenic, or some underlying disease. The majority of bilomas cases are treated by means of drainage p...

By Aleksandra Radovanović, Miljan Krstić, Jasmina Gligorijević, Aleksandra Veličkov, Marko Stojanović

Breast cancer (BC) is the most prevalent and life-threatening malignant tumor in adult females. Little is known about the association between neuropeptide leptin hormone and development of BC. The aim of the paper was to evaluate the interactive role of neuropeptide leptin hormone among BC Jordanian women with regard to treatment exposure and menop...

By Safa'a Al-Zeidaneen, Mousa Ahmad, Ali Al-Ebous

The present study used scientometrics and word co-occurrence analysis to identify the most important topics and to assess trends in English for medical purposes over time. Documents indexed in Scopus and Web of Science were used to examine various indicators such as keywords, countries, organizations, and authors. Search results were preprocessed t...

By Nematullah Shomoossi, Mostafa Rad, Mansoureh Fiezabadi, Esmaeil Vaziri, Mostafa Amiri