Remodeling of the myocardium in patients with primary aldosteronism (PA) is mediated by the presence of mineralocorticoid receptors on the myocytes and fibroblasts. The goal of this study was to analyze the effect of arterial hypertension and metabolic disorders on the cardiovascular system in patients with PA. We recruited 54 patients with PA, 32 ...

By Andryi Nykonenko, Iryna Zubryk, Oleksandr Podluzhnyi, Olrksandr Molodan, Sergii Bukhtii, Oleksandr Nykonenko

Cervical cancer is considered as a common female genital cancer. It is also recognized as the second most frequent cause of cancer-related death among women. It is estimated that in Iran cervical cancer ranks the 4th most frequent cancer in women. Therefore, with regard to the importance of Pap smear in preventing cervical cancer, together with the...

By Bibi Hoseini, Nematullah Shomoossi, Mohammad Rakhshani, Reihane Beinaghi

Sigmoid sinus septic thrombosis is an infrequent complaint that may lead to extensive morbidity and mortality. We report a case with septic thrombosis of the sigmoid sinus caused by chronic mastoiditis and otitis media. A 29-year-old male presented with a 14-day history of tinnitus and true vertigo with a gradually developing swelling on the right ...

By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Zeinab Afshar, Arefeh Babazadeh

Considerable share of patients admitted to the intensive care unit, during the current Covid-19 pandemic, are obese. Obesity is associated with chronic low-grade inflammation, higher endothelial injury, higher levels of angiotensinogen II and increased expression of angiotensin-converting enzyme 2 receptors in the adipose tissue. These alterations ...

By Vesna Marjanović

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

Genetic counselling is a complex process that helps people to understand and adopt medical, psychological and genetic aspects of the disease and enable them to make an appropriate decision. In this framework, we revisited all the existing models for decision-making and suggested their use in the process of genetic counselling, which may lead to mor...

By Marija Lević, Dušanka Krajnović, Valentina Marinković

Anxiety is an inborn emotional and cognitive reaction that enables humans to cope with everyday situations, however, it can be pathological as well. Although Spielberger’s State-Trait Anxiety Inventory (STAI) scales are most frequently used to study the presence/absence of anxiety, there is a lack of empirical studies in Serbian healthy and/o...

By Nikola Stojanović, Pavle Ranđelović, Gordana Nikolić, Nenad Stojiljković, Sonja Ilić, Bogdan Stoiljković, Niko Radulović

The frequency of anxiety disorders has been significantly increasing during the last few decades, especially within the younger population. This review article inclines to explain the differences between fear and anxiety, types of disorders that might mimic anxiety or induce it, and the involvement of different neural circuits in the processing of ...

By Nikola Stojanović, Gordana Nikolić, Milica Todorovska, Pavle Ranđelović, Nenad Stojiljković, Niko Radulović

Summary Influenza is of particular importance because of the pace of epidemics, the extent and number of infected people, and the severity of the side effects. The aim of this study was to investigate the epidemiological and clinical aspects of this disease during the last epidemic in southern Iran. The present cross-sectional study was performed o...

By Alireza Bahonar, Abdolhossein Madani, Vahid Rahmanian, Masihollah Shakeri, Heshmatollah Shakeri, Abdolreza Sotoodeh Jahromi

The plant Mimosa pudica (M. pudica) has been reported by researchers as an anti-inflammatory herb, amongst other properties, but its use as an anticancer herb is still sketchy. This study was aimed at evaluating the n-hexane, butanol and aqueous fractions of M. pudica leaf extract as a chemo-herbal therapy in cadmium-induced hepatocellular tumor. F...

By Monday Felix, Ekiokakpo Patience, Chukwuma Ferdinand, Obari Osaro