Remodeling of the myocardium in patients with primary aldosteronism (PA) is mediated by the presence of mineralocorticoid receptors on the myocytes and fibroblasts. The goal of this study was to analyze the effect of arterial hypertension and metabolic disorders on the cardiovascular system in patients with PA. We recruited 54 patients with PA, 32 ...

By Andryi Nykonenko, Iryna Zubryk, Oleksandr Podluzhnyi, Olrksandr Molodan, Sergii Bukhtii, Oleksandr Nykonenko

Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...

By Nimet Kalkan, Mehmet Tezcan

Sigmoid sinus septic thrombosis is an infrequent complaint that may lead to extensive morbidity and mortality. We report a case with septic thrombosis of the sigmoid sinus caused by chronic mastoiditis and otitis media. A 29-year-old male presented with a 14-day history of tinnitus and true vertigo with a gradually developing swelling on the right ...

By Soheil Ebrahimpour, Mahmoud Sadeghi-Haddad-Zavareh, Zeinab Afshar, Arefeh Babazadeh

Normal development is one of the reliable criteria for the assessment of children's health status. Perinatal events affect the future development of children. Nevertheless, there are different views on the impact of events in the perinatal period on child development. The aim of this study was to determine the relationship between perinatal period ...

By Masoumeh Kaviani, Zhaleh Ranjbaran, Roksana Janghorban

Considerable share of patients admitted to the intensive care unit, during the current Covid-19 pandemic, are obese. Obesity is associated with chronic low-grade inflammation, higher endothelial injury, higher levels of angiotensinogen II and increased expression of angiotensin-converting enzyme 2 receptors in the adipose tissue. These alterations ...

By Vesna Marjanović

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

Postpartum psychiatric disorders are mental disorders which occur after childbirth. Untreated depression and anxiety during pregnancy as well as stress and previous episodes of depression are significant risk factors for postpartum psychiatric disorders. Postpartum blues, postpartum depression and postpartum psychosis, as well as postpartum anxiety...

By Jelena Stojanov, Miodrag Stanković, Olivera Žikić, Jovana Antonijević

During the peripartum period, women are at a greater risk of developing a mental disorder or experiencing an exacerbation of the pre-existing mental disorders. Therapeutic interventions are based primarily on psychotherapy, but if the symptoms are severe and pose a risk to the mother and the child, then the use of drugs, hospitalization or electroc...

By Miodrag Stanković, Jelena Stojanov, Jovana Antonijević

Obesity is an increasing health problem in developing countries and has grown into a major global epidemic. Recent studies suggest that colonization of the stomach with Helicobacter pylori (H. pylori) may affect gastric expression of appetite and satiety-related hormones, finding that patients cured of H. pylori infection have gained weight. Furthe...

By Abdulhadi Alrubaie, Maytham Al-Qanbar, Raed Rassam

Leadership is a tool and a potential power in an organization. Managers would be able to achieve organizational goals and also manage conflicts in a more effective manner by using appropriate leadership styles. The purpose of this study was to investigate the relationship between leadership styles and conflict management among the nurses of Hamadan...

By Zahra Hassanian, Amir Sadeghi, Maryam Farhadi, Amanj Rahrovan