Artificial intelligence (AI) is reshaping personalized medicine by enabling earlier diagnosis, tailored therapies, and faster drug discovery. The aim of the paper was to synthesize current evidence on AI applications in precision healthcare and quantify their impact on diagnostics, therapeutic decision-making, and discovery. We conducted a systemat...

By Marko Kimi Milić, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj

When making complete dentures, both functional and aesthetic criteria need to be met so that the patient can accept the prosthetic restoration more easily and be satisfied with it. The aim of the research was to determine smile parameters as anthropological criteria for the selection of teeth when making complete dentures. The study included 91 den...

By Milena Kostić, Marko Igic, Marija Đorđević, Ermin Đerlek, Ana Pejcic, Nikola Gligorijević, Ivana Stankovic, Nadica S. Đorđević, Marija Andjelkovic Apostolovic

Multiple myeloma is a malignant plasma cell disorder characterized by clonal proliferation of abnormal plasma cells. Global five-year survival rates range from 60% to 70%, largely due to novel therapeutic strategies. In our country, conventional therapies remain standard, with monoclonal antibodies recently introduced for relapsed/refractory cases....

By Dragana Drašković, Goran Marjanović, Miodrag Vučić, Irena Ćojbašić

Retinitis pigmentosa (RP) is a diverse group of inherited retinal diseases characterized by the gradual degeneration of rod and cone photoreceptors in the retina. RP is primarily inherited, with numerous genetic mutations implicated in its pathogenesis. The aim of this study was to summarize the findings of studies related to genes implicated in re...

By Olivia Narváez, Zerón Mendieta, Orlando Torres, Magally Escobar, Martha Trujillo-Güiza

Breast cancer (BC) represents a globally significant health issue, with incidence rates varying worldwide. Radiotherapy is crucial in treating BC, however, it can cause adverse effects, including skin reactions. The aim of this research was to evaluate the impact of two different radiotherapy fractionation regimens on the occurrence and severity of...

By Milica Radić, Andrija Jović, Ana Cvetanović, Ivan Petković, Dane Krtinić, Katarina Krasić, Sandra Radenković, Slavica Stojnev, Irena Conić

Esophagogastric varices develop in 50-60% of patients with liver cirrhosis, and 30% of them have one episode of variceal hemorrhage within two years of variceal diagnosis. The aim of the paper was to present the latest attitudes in the treatment of esophagogastric varices. Literature review. Prevention of first bleeding from esophageal varices (EV)...

By Ivan Grgov, Daniela Benedeto-Stojanov, Biljana Radovanović-Dinić, Milica Grgov, Saša Grgov, Tomislav Tasić

Although we could not find the registered cases of leptospirosis co-occurring with lymphogranulomatosis, it is important to note that both diseases can affect the immune system. Therefore, the reported case is unique and will be interesting and useful for the physicians of various specialties. We report a case of icterohemorrhagic form of leptospir...

By Borys Fylenko, Ivan Starchenko, Nataliia Roiko, Iryna Kornilova, Anatolii Romanyuk, Mykola Lyndin

Immune checkpoint inhibitors (ICIs) immensely improved outcomes in melanoma patients. Vitiligo-like depigmentation (VLD) is a well-documented adverse event of ICIs which is well tolerated and often associated with prolonged response to treatment. The aim of this study was to assess the effect of VLD occurrence on survival in melanoma patients treat...

By Aleksandar Popović, Ana Stojković, Ana Cvetanović, Andrija Jović, Milica Radić, Irena Conić, Ivan Petković

Multiple myeloma is the second most common hematological malignancy in which pathological plasma cells secrete monoclonal proteins, ultimately leading to end-organ damage. Albumin, β2-microglobulin, and LDH are considered highly relevant biomarkers for the diagnosis and prognosis of this disease. There are different types of treatment availabl...

By Ina Konstantinović, Irena Ćojbašić, Miodrag Vučić

Unhealthy eating habits and a lack of physical activity are well-known risk factors for chronic illnesses, and many countries in transition have struggled to make significant progress in addressing diet-related non-communicable diseases. Education about diet and nutrition is important for public health, and healthcare professionals are essential in...

By Bojana Miladinović, Milica Milutinović, Dušanka Kitić, Milica Randjelović, Nikolina Savić, Katarina Simonović, Maja Nikolić