Esophagogastric varices develop in 50-60% of patients with liver cirrhosis, and 30% of them have one episode of variceal hemorrhage within two years of variceal diagnosis. The aim of the paper was to present the latest attitudes in the treatment of esophagogastric varices. Literature review. Prevention of first bleeding from esophageal varices (EV)...

By Ivan Grgov, Daniela Benedeto-Stojanov, Biljana Radovanović-Dinić, Milica Grgov, Saša Grgov, Tomislav Tasić

Wernicke encephalopathy is a rare acute/subacute neurological disorder, commonly caused by prolonged thiamine deficiency in patients who chronically consume alcohol. According to the Caine classification criteria, the clinical diagnosis of this encephalopathy involves at least two of the following four signs: nutritional deficiency, oculomotor dysf...

By Aleksandra Lučić-Prokin, Vladimir Galić, Timea Kokai-Zekić, Vedran Žigić

Oral mucositis is an acute, inflammatory, and ulcerative condition of the oral mucosa caused by chemotherapy and/or radiotherapy. Considering the frequency of oral mucositis, its impact on the physical and mental health of patients, as well as the depletion of the economic capacities of an individual and society, the importance of prevention and ma...

By Bojan Poposki, Kiro Ivanovski, Ana Pejčić, Vlatko Kokolanski, Ivana Stanković

Perinatal asphyxia (PA) is a condition in which there is a decreased or interrupted blood and oxygen supply to the tissues of the fetus, i.e., the newborn, immediately before, during, or immediately after delivery. It constitutes a significant cause of mortality, accounting for 23-24% of all neonatal deaths. The estimated global incidence of perina...

By Dejan Dobrijević, Biljana Vučković, Jasmina Katanić

Although we could not find the registered cases of leptospirosis co-occurring with lymphogranulomatosis, it is important to note that both diseases can affect the immune system. Therefore, the reported case is unique and will be interesting and useful for the physicians of various specialties. We report a case of icterohemorrhagic form of leptospir...

By Borys Fylenko, Ivan Starchenko, Nataliia Roiko, Iryna Kornilova, Anatolii Romanyuk, Mykola Lyndin

Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

Parkinson's disease (PD) is a chronic, neurodegenerative disorder that in certain stages can present a series of acute symptoms and signs, the development of which lasts several hours or days. Emergencies in PD can be a direct consequence of the pathophysiology of the disease or a secondary consequence of the administration of antiparkinsonian drug...

By Jelena Stamenović, Vuk Milošević, Vanja Đurić

Type 2 diabetes mellitus (T2DM) is characterized by impaired glycemic control, which increases the risk of cardiovascular and metabolic complications. Exercise is a key non-pharmacological intervention known to improve blood glucose regulation, but the acute effects of different exercise modalities on glycemic control in T2DM remain unclear. The ai...

By Anja Lazić, Tatjana Jevtovic Stoimenov, Nebojša Trajković

Approximately 50% of embryo transfer cycles are performed as frozen embryo transfer (FET) cycles; however, research on the factors influencing pregnancy rates in these cycles is limited in northern Iran. The aim of this study was to identify the factors influencing the clinical pregnancy rate in hormone replacement therapy (HRT) FET cycles among in...

By Sepideh Peivandi, Samaneh Aghajanpour, Mohammad Khademloo, Keshvar Samadaee Gelehkolaee, Marzieh Zamaniyan

The emergence of the COVID-19 pandemic has underscored the critical importance of accurate and reliable methods for the early detection and management of cases. Traditional approaches to COVID-19 diagnosis often rely on binary classification methods, which may limit their accuracy and robustness. In this study, we propose a novel approach that leve...

By Affaf Khaouane, Latifa KHAOUANE, Samira FERHAT, Salah HANINI