Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

The emergence of the COVID-19 pandemic has underscored the critical importance of accurate and reliable methods for the early detection and management of cases. Traditional approaches to COVID-19 diagnosis often rely on binary classification methods, which may limit their accuracy and robustness. In this study, we propose a novel approach that leve...

By Affaf Khaouane, Latifa Khaouane, Samira Ferhat, Salah Hanini

Artificial intelligence (AI) is reshaping personalized medicine by enabling earlier diagnosis, tailored therapies, and faster drug discovery. The aim of the paper was to synthesize current evidence on AI applications in precision healthcare and quantify their impact on diagnostics, therapeutic decision-making, and discovery. We conducted a systemat...

By Marko Kimi Milić, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al

Burns represent one of the leading causes of morbidity and mortality in children. Aim. Aim of this review is to gain better understand of the pathophysiological changes and assessment of the severity of burn injuries in different ages of pediatric patients, which may help in early implementation of appropriate therapeutic procedures and improvement...

By Vesna Marjanović

Perinatal asphyxia (PA) is a condition in which there is a decreased or interrupted blood and oxygen supply to the tissues of the fetus, i.e., the newborn, immediately before, during, or immediately after delivery. It constitutes a significant cause of mortality, accounting for 23-24% of all neonatal deaths. The estimated global incidence of perina...

By Dejan Dobrijević, Biljana Vučković, Jasmina Katanić

Esophagogastric varices develop in 50-60% of patients with liver cirrhosis, and 30% of them have one episode of variceal hemorrhage within two years of variceal diagnosis. The aim of the paper was to present the latest attitudes in the treatment of esophagogastric varices. Literature review. Prevention of first bleeding from esophageal varices (EV)...

By Ivan Grgov, Daniela Benedeto-Stojanov, Biljana Radovanović-Dinić, Milica Grgov, Saša Grgov, Tomislav Tasić

Behçet’s disease is a systemic, chronic, idiopathic inflammatory illness of unknown etiology with a recurrent course, manifested by a characteristic triad: recurrent aphthous stomatitis, ulcerative changes in the mucous membranes and skin of the genital organs, and inflammatory changes in the eyes. In addition, the musculoskeletal syst...

By Vita Ruzhanska, Iuliia Pashkova, Dmytro Grebeniuk, Andrii Sidorov, Svitozar Prevar, Oleksandr Smiiukha, Yuriy Hnatiyk, Arina Ivanitsa

Seat belt syndrome (SBS) is a new pattern of injuries in road traffic accidents (RTAs). It refers to injuries caused by the interaction of the human body and the safety belt and consists of a wide spectrum of injuries (musculoskeletal and visceral). In this paper, we present a case of a front-seat passenger with polytrauma sustained in an RTA, who,...

By Slađana Anđelić, Eleftheria Papadopoulou, Tanja Nikolić, Goran Čolaković, Milena Popović

Immune checkpoint inhibitors (ICIs) immensely improved outcomes in melanoma patients. Vitiligo-like depigmentation (VLD) is a well-documented adverse event of ICIs which is well tolerated and often associated with prolonged response to treatment. The aim of this study was to assess the effect of VLD occurrence on survival in melanoma patients treat...

By Aleksandar Popović, Ana Stojković, Ana Cvetanović, Andrija Jović, Milica Radić, Irena Conić, Ivan Petković