Lower airways are sterile, but many researchers have reported the existence of bronchial colonization with pathogenic and non-pathogenic microorganisms in smokers and patients with chronic obstructive pulmonary disease (COPD) and lung cancer. The aim of this study was to determine the existence and type of bronchial colonization in patients with no...

By Ana Stojanović

Stress is defined as a state in which homeostasis, as a dynamic balance of internal conditions necessary for the proper functioning of cells or the living organism as a whole, is affected by the action of various stressors. Stress reaction occurs as a result of stress system activities, which is located in the central and peripheral nervous system....

By Nedeljka Ivković, Đorđe Božović, Maja Račić, Dijana Popović-Grubač, Brankica Davidović

The application of anthracycline and trastuzumab in adjuvant breast cancer treatment approach has significantly improved the survival of patients, but also carries the risk of cardiotoxicity that is manifested by reducing the ejection fraction of the heart. The aim of the study was to investigate the effect of cumulative anthracycline dose in combi...

By Ivana Krstić, Marina Deljanin Ilić, Svetislav Vrbić, Ivica Pejčić

Leech therapy is likely to cause symptomatic relief in migraine headache sufferers, but there is little clinical data in this field. This study aimed to investigate the effectiveness of leech therapy in the management of migraine headaches. This is a quasi-experimental pilot study with a three-month post-treatment follow-up. Twenty-six patients wit...

By Mahmoud Bakhshi, Babak Jalalian, Maryam Valian, Saeide Shariati, Tahere Saeidi, Hossein Ranjbar

Peutz-Jeghers syndrome (PJS) is a rare genetic disorder with autosomal-dominant pleiotropic inheritance, variable penetrance and characteristic signs of the disease that predisposes persons to increased risk of developing cancer, particularly in the gastrointestinal tract and the breast. Due to genetic nature of disease, in the familial Peutz-Jeghe...

By Marijola Mojsilović, Vuka Katić, Ivan Ilić, Biljana Radovanović, Bratislav Petrović, Miodrag Lazić, Marijana Krstić

The pathophysiology of periapical lesions (PLs) is under control of pro-inflammatory and anti-inflammatory (mainly immunoregulatory) cytokines. We have recently established mesenchymal stem cells (MSCs) from PLs and showed their suppressive effects on the production of proinflammatory cytokines from PLs inflammatory cells (ICs). In this work we stu...

By Milan Marković, Sergej Tomić, Jelena Djokić, Miodrag Čolić

The aim of the paper was to investigate the tissue response to the implantation of "Endomethasone" (Septodont) in artificially prepared defect in the rat mandible. Sixteen Wistar male rats were used for the experiment. After anesthesia, a defect between the midline and the mental foramen of the left mandible was made (diameter 1.4 mm, 1.6 mm depth)...

By Marija Nikolić, Jovanka Gašić, Aleksandar Mitić, Jelena Popović, Aleksandra Radovanović, Radomir Barac

For more than three decades, assisted reproductive techniques (ART) have been used as effective treatments to overcome infertility. Since then, numerous studies have been focused on different aspects of long-term health and development of children born after assisted conception. The aim of this paper is to summarize new data on multiple pregnancy a...

By Milena Milićević, Srećko Potić

Cemento-enamel junction (CEJ) is an important anatomical structure of the tooth, which is located in the cervical part of the tooth between the crown and root, or at the contact point between the enamel which overlaps the tooth crown and cementum overlapping the root dentin. There are four possible relationships between two tissues that make the CE...

By Nenad Stošić, Stefan Dačić, Dragica Dačić Simonović

Milk contains plenty of enzymatic and non-enzymatic antioxidant components that probably account for the vital antioxidant protection of the infants at early stages of life against the development of complications induced by oxygen free radicals. Indigenous milk enzymes play a key role in regulating lactogenesis, including active involution of mamm...

By Jelena Živković, Slavica Sunarić, Nataša Trutić, Marko Denić, Gordana Kocić, Tatjana Jovanović