The aim of the paper was to determine the factors related to the initial therapy that may contribute to death from severe necrotizing acute pancreatitis and to analyze their clinical importance as well as possible additive effects. A retrospective case-control study included all adult patients treated for severe necrotizing acute pancreatitis in th...

By Ivan Praznik, Marko Spasić, Ivan Radosavljević, Bojan Stojanović, Dragan Čanović, Dragče Radovanović, Zorica Savović, Radiša Vojinović, Živan Babić, Nela Đonović, Tanja Luković, Predrag Lazarević, Nataša Đorđević, Irena Kostić, Ivana Jelić, Jelena Petrović, Stefan Stojanović, Milena Jurišević, Iva Grubor, Ljiljana Nikolić, Ksenija Vučićević, Viktorija Artinović, Anđela Milojević, Marina Kostić, Srđjan Stefanović, Slobodan Janković

Ameloblastoma, a semi-benign odontogenic tumor, is divided into four subtypes based on the clinical presentation, radiological manifestations and histological characteristics. Radiologically, it manifests itself in the form of uni- or multicystic intrabony expansive lesions, with destruction of the medullary zone of the existing bone, resorption an...

By Miloš Trajković, Dragan Krasić, Milan Spasić, Miljan Krstić, Miloš Stojanović, Vojkan Lazić

Rutin (quercetin-3-O-rutinoside) is one of the most abundant bioflavonoids with various biological and pharmacological activities. Considering the ubiquitous presence of Mg(II) and Ca(II) ions in biological systems we decided to investigate their influence on the autoxidation of rutin in weakly alkaline aqueous solutions. Changes in UV-Vis spectra ...

By Slavoljub C. Živanović, Ružica S. Nikolić, Goran M. Nikolić

This study was undertaken to determine the antidiabetic and antioxidant effects of oral administration of ethanolic extract of Moringa oleiferaflower on stretozotocin-induced diabetic rats at 100, 200, and 300 mg/kg b.w. Thirty (30) male experimental albino rats were grouped randomly into six groups: groups A, B, and F are the control, diabetic con...

By Rotimi Olusanya Arise, Oluwaseun Ruth Aburo, Samuel Tobi Farohunbi, Adenike Adebola Adewale

Statins are drugs that are well tolerated, but considering their extensive use, there are still concerns regarding their safety. Knowledge of patients about the side effects of statins has not been adequately studied, although timely recognition of the AES is of vital importance for improving the quality of patient care and reducing morbidity and s...

By Valentina Opančina, Slobodan Janković, Gordana Stanić, Miljan Opančina

Stress is defined as a state in which homeostasis, as a dynamic balance of internal conditions necessary for the proper functioning of cells or the living organism as a whole, is affected by the action of various stressors. Stress reaction occurs as a result of stress system activities, which is located in the central and peripheral nervous system....

By Nedeljka Ivković, Đorđe Božović, Maja Račić, Dijana Popović-Grubač, Brankica Davidović

The application of anthracycline and trastuzumab in adjuvant breast cancer treatment approach has significantly improved the survival of patients, but also carries the risk of cardiotoxicity that is manifested by reducing the ejection fraction of the heart. The aim of the study was to investigate the effect of cumulative anthracycline dose in combi...

By Ivana Krstić, Marina Deljanin Ilić, Svetislav Vrbić, Ivica Pejčić

Leech therapy is likely to cause symptomatic relief in migraine headache sufferers, but there is little clinical data in this field. This study aimed to investigate the effectiveness of leech therapy in the management of migraine headaches. This is a quasi-experimental pilot study with a three-month post-treatment follow-up. Twenty-six patients wit...

By Mahmoud Bakhshi, Babak Jalalian, Maryam Valian, Saeide Shariati, Tahere Saeidi, Hossein Ranjbar

The aim of the paper was to investigate the tissue response to the implantation of "Endomethasone" (Septodont) in artificially prepared defect in the rat mandible. Sixteen Wistar male rats were used for the experiment. After anesthesia, a defect between the midline and the mental foramen of the left mandible was made (diameter 1.4 mm, 1.6 mm depth)...

By Marija Nikolić, Jovanka Gašić, Aleksandar Mitić, Jelena Popović, Aleksandra Radovanović, Radomir Barac

For more than three decades, assisted reproductive techniques (ART) have been used as effective treatments to overcome infertility. Since then, numerous studies have been focused on different aspects of long-term health and development of children born after assisted conception. The aim of this paper is to summarize new data on multiple pregnancy a...

By Milena Milićević, Srećko Potić