Targeting inflammation: Cohort study of the influence of methotrexate therapy on sideropenic anemia and reduction of inflammatory markers in rheumatoid arthritis patients
Rheumatoid arthritis (RA) is a systemic autoimmune disease that can cause destructive joint disease and progressive disability. The diagnosis of RA is based on laboratory and clinical evidence, which includes the analysis of inflammatory markers, hematological, and biochemical parameters. Fifty patients diagnosed with RA without methotrexate (MTX) ...
By Maja Mitrašinović-Brulić, Ema Maslo, Muhamed Fočak, Damir Suljević
A severe case of snakebite envenoming by Vipera ammodytes in winter
Venomous snakebites in Serbia are neither too frequent nor extremely dangerous. Nevertheless, some can lead to complications or even death. On December 24, 2023, a young man was admitted to hospital after being bitten by a snake, believed to be Vipera ammodytes. He was in a state of shock, unconscious, with unmeasurable blood pressure. Having recei...
By Slađana Pavić, Sonja Nikolić
Hepatorenal toxicity of different doses of ketorolac administration in adult male rats: A preclinical study
Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...
By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi
N-terminal pro-brain natriuretic peptide superiority for prognosis of major adverse cardiovascular events in patients with acute myocardial infarction without heart failure
Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...
By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević
ISOLATED RIGHT FALLOPIAN TUBE TORSION IN A 13-YEAR-OLD ADOLESCENT
Isolated fallopian tube torsion is a rare condition, especially in adolescents, and can often be misdiagnosed due to nonspecific symptoms. We report the case of a 13-year-old sexually inactive girl who was admitted to Shahid Mobini Hospital in Sabzevar, Iran, with worsening pain in the right lower abdomen and hypogastrium over the past four d...
By Behnaz Souizi, Mehrnaz Mehrdoost, Marzie Torkmannejad Sabzevari, Narjes Forouhar
EPILEPSY IN CHILDREN WITH CENTRAL NERVOUS SYSTEM INFECTIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS
In childhood, infections of the central nervous system may lead to neurodevelopmental disorders and complications such as epilepsy. The present study aimed to evaluate epilepsy in children with central nervous system (CNS) infections. The present systematic review and meta-analysis included five cohort studies from international databases, PubMed, ...
By Mahsa Afrand, Niusha Rostampur, Zeinab Pourhadi, Javad Rezanezhad, Pouriya Nekoueifard
Successful treatment response in a patient with severe neurological manifestations of drug-induced acute intermittent porphyria: A case report
Acute intermittent porphyria is a rare metabolic disorder of the hem biosynthetic pathway that can cause severe neurological symptoms involving the central, autonomic and peripheral nervous system. Diagnosis may be delayed due to variable symptoms that can mimic other diseases. A 23-year-old woman with abdominal pain, constipation, progressive deve...
By Stefan Todorović, Gordana Đorđević, Andrija Rančić, Dejan Aleksić
Skin challenges in COVID-19 pandemic: The importance of cosmeceuticals
Although COVID-19 is present in a milder form nowadays, systemic disorders caused by the virus lead to multiple organ malfunctions. Skin manifestations are the consequence of the disease itself but also the result of preventative measures taken to avoid the infection. They generally do not require pharmacotherapy except in severe cases. Depending o...
By Marija Tasić-Kostov
Acute myocardial infarction in patients under forty-five years of age: What has changed in ten years?
The incidence of acute myocardial infarction (AMI) is declining in developed countries due to better prevention and more effective treatment of risk factors, however, the proportion of younger patients with AMI is increasing. The aim of the research was to compare patients under the age of 45 years with acute myocardial infarction at a ten-year int...
By Danijela Đorđević-Radojković, Miodrag Damjanović, Svetlana Apostolović, Jelena Milošević, Dragana Stanojević, Goran Koraćević, Ružica Janković-Tomašević, Tomislav Kostić, Sonja Dakić, Jelena Cvetković, Jovana Šarić
Breaking the silence: Innovative approaches to voice rehabilitation and communication for laryngectomized patient
Laryngectomy is a surgical procedure for the removal of the larynx, either entirely (total laryngectomy) or partially (partial laryngectomy). Rehabilitation of laryngectomy patients is a complex process that involves physical, psychological, and social aspects. To improve the quality of life of laryngectomy patients, rehabilitation consists of seve...
By Dina Rujević, Mirjana Petrović-Lazić