Although diffuse large B-cell lymphoma (DLBCL) represents a paradigm of highly curative disease with a complete remission (CR) rate of ≈ 60%–70% in an upfront setting, the remaining 30%–40% of patients present a relapse/refractory setting. These population are highly critical and amended for salvage treatment approach. Novel appro...

By Ivan Petković, Marija Elez, Aleksandar Popović, Slavica Stojnev, Irena Conic, Miljana Džunić, Dane Krtinić

When making complete dentures, both functional and aesthetic criteria need to be met so that the patient can accept the prosthetic restoration more easily and be satisfied with it. The aim of the research was to determine smile parameters as anthropological criteria for the selection of teeth when making complete dentures. The study included 91 den...

By Milena Kostić, Marko Igic, Marija Đorđević, Ermin Đerlek, Ana Pejcic, Nikola Gligorijević, Ivana Stankovic, Nadica S. Đorđević, Marija Andjelkovic Apostolovic

Multiple myeloma is a malignant plasma cell disorder characterized by clonal proliferation of abnormal plasma cells. Global five-year survival rates range from 60% to 70%, largely due to novel therapeutic strategies. In our country, conventional therapies remain standard, with monoclonal antibodies recently introduced for relapsed/refractory cases....

By Dragana Drašković, Goran Marjanović, Miodrag Vučić, Irena Ćojbašić

There are no specific risk factors for stroke after bee or wasp stings; however, several researchers have cited multiple stings in the head and neck region as a significant factor in the occurrence of these serious complications. We present a case of a previously healthy man with multiple acute cerebral infarctions in the subcortical and borderline...

By Vekoslav Mitrović, Snezana Lazic, Bratislav Lazic, Radojica Stolić

The aim of this study was to examine whether green tea and bilberry have beneficial effects on secondary hyperlipidemia developed due to gentamicin-induced renal impairment. GM group of rats was treated with gentamicin only, GT group was given green tea only, B group received bilberry only, while C group was given saline only. GT+GM group received ...

By Milica Veljković, Nikola M. Stojanović, Tanja Džopalić, Dragana R. Pavlović, Dušan Sokolović, Milan Petković

Naturally-derived anti-inflammatories, such as bilberry (Vaccinium myrtillus), are particularly interesting due to their health benefits. Bilberries are a rich source of primary metabolites such as sugars and organic acids, which give the fruit its taste. They also contain anthocyanins, the most abundant group of secondary metabolites, possessing v...

By Anđela V. Dragićević, Nikola M. Stojanović, Dragana R. Pavlović

The emergence of the COVID-19 pandemic has underscored the critical importance of accurate and reliable methods for the early detection and management of cases. Traditional approaches to COVID-19 diagnosis often rely on binary classification methods, which may limit their accuracy and robustness. In this study, we propose a novel approach that leve...

By Affaf Khaouane, Latifa Khaouane, Samira Ferhat, Salah Hanini

Type 2 diabetes mellitus (T2DM) is characterized by impaired glycemic control, which increases the risk of cardiovascular and metabolic complications. Exercise is a key non-pharmacological intervention known to improve blood glucose regulation, but the acute effects of different exercise modalities on glycemic control in T2DM remain unclear. The ai...

By Anja Lazić, Tatjana Jevtovic Stoimenov, Nebojša Trajković

Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

Artificial intelligence (AI) is reshaping personalized medicine by enabling earlier diagnosis, tailored therapies, and faster drug discovery. The aim of the paper was to synthesize current evidence on AI applications in precision healthcare and quantify their impact on diagnostics, therapeutic decision-making, and discovery. We conducted a systemat...

By Marko Kimi Milić, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj